Coconut oil intake and its effects on the cardiometabolic profile – A structured literature review

Santos, Heitor O.; Howell, Scott; Earnest, Conrad P.; Teixeira, Filipe J.

doi:10.1016/j.pcad.2019.11.001

Cited by 39 publications

(30 citation statements)

References 68 publications

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“…In general, coconut oil ingestion is thought to increase HDL [44]. Lauric acid, which accounts for about 50% of the coconut oil content, is proposed to be the cornerstone of the pathway.…”

Section: Discussionmentioning

confidence: 99%

High-fat diet-induced obesity and impairment of brain neurotransmitter pool

Labban

Alfawaz

Almnaizel

et al. 2020

Translational Neuroscience

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AbstractObesity and the brain are linked since the brain can control the weight of the body through its neurotransmitters. The aim of the present study was to investigate the effect of high-fat diet (HFD)-induced obesity on brain functioning through the measurement of brain glutamate, dopamine, and serotonin metabolic pools. In the present study, two groups of rats served as subjects. Group 1 was fed a normal diet and named as the lean group. Group 2 was fed an HFD for 4 weeks and named as the obese group. Markers of oxidative stress (malondialdehyde, glutathione, glutathione-s-transferase, and vitamin C), inflammatory cytokines (interleukin [IL]-6 and IL-12), and leptin along with a lipid profile (cholesterol, triglycerides, high-density lipoprotein, and low-density lipoprotein levels) were measured in the serum. Neurotransmitters dopamine, serotonin, and glutamate were measured in brain tissue. Fecal samples were collected for observing changes in gut flora. In brain tissue, significantly high levels of dopamine and glutamate as well as significantly low levels of serotonin were found in the obese group compared to those in the lean group (P > 0.001) and were discussed in relation to the biochemical profile in the serum. It was also noted that the HFD affected bacterial gut composition in comparison to the control group with gram-positive cocci dominance in the control group compared to obese. The results of the present study confirm that obesity is linked to inflammation, oxidative stress, dyslipidemic processes, and altered brain neurotransmitter levels that can cause obesity-related neuropsychiatric complications.

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“…In general, coconut oil ingestion is thought to increase HDL [44]. Lauric acid, which accounts for about 50% of the coconut oil content, is proposed to be the cornerstone of the pathway.…”

Section: Discussionmentioning

confidence: 99%

High-fat diet-induced obesity and impairment of brain neurotransmitter pool

Labban

Alfawaz

Almnaizel

et al. 2020

Translational Neuroscience

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“…It is possible to observe that the oilcrops listed above have distinct fatty acid compositions ( Table 2). Among them, Licuri oil is the only one that has more saturated than unsaturated fatty acids in its composition, and one has to take some care regarding its ingestion to obey the medical guideline recommendations for saturated fatty acids, the intake of which should not exceed 10% total daily energy [55]. On the other hand, Licuri oil is rich in the medium chain lauric acid and it could be an interesting oil source for the oleochemical industry and for the obtention of lipid-based formulations with various applications in pharmaceutical products and cosmetics [56; 57; 58].…”

Section: Oil Content Fatty Acid Composition Additional Bioactive Comentioning

confidence: 99%

Oleochemistry potential from Brazil northeastern exotic plants

et al. 2020

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Caatinga is a Brazilian semi-arid ecosystem that stands out for presenting unique environmental characteristics with a dry, spiny and deciduous shrub/forest vegetation with several species that can be renewable oil sources with potential applicability in oleochemical and nutrition. Caatinga oilseeds have a high content of unsaturated fatty acids, phytosterols and sterols, and this composition is related to its nutritional potential. The present review summarizes the knowledge on the oil contents and fatty acid profiles of seeds from six representatives caatinga species. It was observed that plants species like Caju (Anacardium occidentale L.), Favela (Cnidoscolus quercifolius Pohl), Licuri (Syagrus coronata (Mart.) Becc.), Pinhão-bravo (Jatropha mollissima Pohl Baill), Pequi (Caryocar brasiliense Camb) and Oiticica (Licania rígida Benth) contains approximately 33.1, 33.5, 49.2, 18.3, 70.16 and 57.0 % w/w of oil, respectively, on a dry weight basis. Their fatty acid profiles are mostly saturated for Licuri oil, with a high content of lauric acid (up to 40%) and unsaturated for Favela, Pinhão-bravo, Cashew nut, Pequi and Oiticica oils. Oiticica oil shows a high concentration of unusual conjugated polyunsaturated fatty acids, like α-Eleostearic and Licanic acid with 16.90 and 43.20 % w/w, respectively.

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“…Coconut oil (CO) is extracted from coconut fruits (Cocos nucifera) and represents a font of saturated fat containing high levels of lauric acid, a medium chain fatty acid [6]. In recent years, health professionals and laypeople have disseminated uncertain information about CO consumption to control MS and NASH.…”

Section: Abbreviationsmentioning

confidence: 99%

“…However, the ability of CO to promote atherosclerosis through other pathways has also been questioned [8]. Some studies indicate that excessive consumption of coconut oil may be associated with the development of MS [6]. Moreover, recent studies associated diets containing CO with health damage, mainly due to cardiovascular complications related to the rising levels of LDL and VLDL and reduced HDL levels [10,11].…”

Section: Co and Msmentioning

confidence: 99%

“…These two mechanisms together make medium chain saturated fatty acids potent agents in the induction of hepatic steatosis, leading to oxidative stress and inflammation [24]. In addition, lauric acid increases LDL levels, since it plays a central role as a substrate for apolipoprotein (apo) A1 and apo B synthesis, which are the key molecules in LDL particles [6].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Can Coconut Oil Promote Non-Alcoholic Steatohepatitis and Metabolic Syndrome? A Timely Review

Cl¹,

S²,

J³

et al. 2020

Clin Med Rev Case Rep

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Metabolic syndrome (MS) and non-alcoholic steatohepatitis (NASH) have been associated with bad eating habits. Supplementation with coconut oil (CO) has been proposed to control these conditions, as some authors suggest that CO provides weight loss and cardiovascular protective effects. However, the effectiveness and safety of emerging diets, such as CO, remain uncertain. This review focuses on the utilization of CO in the control of MS and NASH, besides in addition to describing this cardiovascular and weight loss effects, with special attention to the possible unfavourable impacts on human health, based on clinical and experimental studies.

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Coconut oil intake and its effects on the cardiometabolic profile – A structured literature review

Cited by 39 publications

References 68 publications

High-fat diet-induced obesity and impairment of brain neurotransmitter pool

High-fat diet-induced obesity and impairment of brain neurotransmitter pool

Oleochemistry potential from Brazil northeastern exotic plants

Can Coconut Oil Promote Non-Alcoholic Steatohepatitis and Metabolic Syndrome? A Timely Review

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