Coeliac Disease and Malignancy

Swinson, C M; Coles, E; Slavin, G; Booth, C. C.

doi:10.1016/s0140-6736(83)91754-3

Cited by 405 publications

(190 citation statements)

References 11 publications

Supporting

Mentioning

175

Contrasting

Unclassified

Order By: Relevance

“…The failure of pancreatic enzyme secretion results in abnormal small bowel contents and this is combined with abnormal bile acid metabolism (Weizman et al, 1986), altered mucosal enzymes (Morin et al, 1976) and impaired mucosal absorption (Fondacaro et al, 1982). Steatorrhoea in non-CF patients has also been associated with adenocarcinoma or lymphoma of the jejunum (Swinson et al, 1983).…”

Section: Discussionmentioning

confidence: 99%

A cohort study of cystic fibrosis and malignancy

Sheldon

Hodson²,

Carpenter³

et al. 1993

Br J Cancer

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

A cohort study of cystic fibrosis and malignancy

Sheldon

Hodson²,

Carpenter³

et al. 1993

Br J Cancer

View full text Add to dashboard Cite

show abstract

“…Enteropathy-associated T-cell lymphoma is an aggressive disorder frequently associated with celiac disease [38,39]. Patients with celiac disease have an increased risk of various malignancies [38], including adenocarcinoma of the small bowel and diffuse large B-cell lymphoma.…”

Section: Enteropathy-associated T-cell Lymphomamentioning

confidence: 99%

“…Patients with celiac disease have an increased risk of various malignancies [38], including adenocarcinoma of the small bowel and diffuse large B-cell lymphoma. It is important to remember that a patient with known celiac disease who develops what appears to be a lymphoma in the small bowel might not have enteropathy-associated T-cell lymphoma.…”

Section: Enteropathy-associated T-cell Lymphomamentioning

confidence: 99%

The aggressive peripheral T‐cell lymphomas: 2015

Armitage

2015

American J Hematol

View full text Add to dashboard Cite

Background: T‐cell lymphomas make up approximately 10%–15% of lymphoid malignancies. The frequency of these lymphomas varies geographically, with the highest incidence in parts of Asia.Diagnosis: The diagnosis of aggressive peripheral T‐cell lymphoma (PTCL) is usually made using the World Health Organization classification. The ability of hematopathologists to reproducibly diagnosis aggressive PTCL is lower than that for aggressive B‐cell lymphomas, with a range of 72%–97% for the aggressive PTCLs.Risk Stratification: Patients with aggressive PTCL are staged using the Ann Arbor Classification. Although somewhat controversial, positron emission tomography scans seem to be useful as they are in aggressive B‐cell lymphomas. The most commonly used prognostic index is the International Prognostic Index. The specific subtype of aggressive PTCL is an important risk factor, with the best survival seen in anaplastic large‐cell lymphoma—particularly young patients with the anaplastic lymphoma kinase positive subtype.Risk‐Adapted Therapy: Anaplastic large‐cell lymphoma is the only subgroup to have a good response to a CHOP‐like regimen. Angioimmunoblastic T‐cell lymphoma has a prolonged disease‐free survival in only ∼20% of patients, but younger patients who have an autotransplant in remission seem to do better. PTCL‐not otherwise specified is not one disease. Anthracycline‐containing regimens have disappointing results, and a new approach is needed. Natural killer/T‐cell lymphoma localized to the nose and nasal sinuses seems to be best treated with radiotherapy‐containing regimens. Enteropathy‐associated PTCL and hepatosplenic PTCL are rare disorders with a generally poor response to therapy, although selected patients with enteropathy‐associated PTCL seem to benefit from intensive therapy. Am. J. Hematol. 90:666–673, 2015. © 2015 Wiley Periodicals, Inc.

show abstract

“…1,2 Several autoimmune diseases predispose to lymphoma, with a typical latency of 10-20 yearsFsuch as Hashimoto's thyroiditis, [3][4][5] Sjö gren's syndrome, 6,7 and coeliac disease. 8,9 Inflammatory glandular destruction and MALT acquisition in Sjö gren's syndrome renders such patients about 44 times more likely to develop late-onset marginal zone lymphoma (MZL) in affected tissues. 7 Lymphocyte accrual during the chronic inflammation of Hashimoto's thyroiditis predisposes to later lymphoma (most commonly follicle centre cell variant 4 ) and intestinal lymphomas arising with coeliac disease (typically 7 years after onset 8 ) are predominantly of high-grade T-cell histology.…”

Section: Introductionmentioning

confidence: 99%

“…8,9 Inflammatory glandular destruction and MALT acquisition in Sjö gren's syndrome renders such patients about 44 times more likely to develop late-onset marginal zone lymphoma (MZL) in affected tissues. 7 Lymphocyte accrual during the chronic inflammation of Hashimoto's thyroiditis predisposes to later lymphoma (most commonly follicle centre cell variant 4 ) and intestinal lymphomas arising with coeliac disease (typically 7 years after onset 8 ) are predominantly of high-grade T-cell histology. 9 The chronic inflammation of gastric MALT due to Helicobacter pylori infection, although not autoimmune, also predisposes to the emergence 10,11 and eradication of the infection can lead to disease regression.…”

Section: Introductionmentioning

confidence: 99%