Coexistence Of Biofilm Formation And Antibiotic Resistance Profile Of Uropathogenic E. Coli (Upec)

Abstract

The bacteria known as Uropathogenic Escherichia coli (UPECs) play a major role in triggering UTIs (UTIs). Antibiotic resistanceamong UPEC strains may progress faster if UTIs in Anbar continue to be treated with beta-lactam antibiotics without antibioticsusceptibility testing. In a study evaluating cephalosporin-resistance among 141 E. coli clinical isolates, 100 were found in urinesamples. Antibiotic resistance was analyzed using the VITEK-2 system. The results indicated that resistant to most β-lactamases usedin this study was associated with biofilm formation. 88.5% of UPEC isolates that showed biofilm positive were resist to 3rd generationcephalosporins with a statistically highly significance (P=<0.0001).

Predictors of antibiogram performance and antibiotic resistance patterns in the northern Syrian region: A cross-sectional investigation

“…34 In addition, research concerning uropathogenics reported a connection between biofilm development and resistance to third-generation cephalosporins. 35 Escherichia coli exhibited high sensitivity to meropenem, amikacin, nitrofurantoin, levofloxacin, and gentamicin, in agreement with a previous study showing significant resistance to fluoroquinolones, despite their high susceptibility to imipenem, meropenem, tazobactam, cefoperazone + sulbactam, and amikacin. 36 In the present study, all identified pathogens exhibited significant resistance to third-generation cephalosporins, including ceftriaxone, cefotaxime, and cefixime.…”

Relationship between antimicrobial resistance and virulence factors in uropathogenic Escherichia coli isolates from Ramadi, Iraq: phenotype and genotype identification

“…Recently, most attention is paid to blaTEM genes that are carried on the plasmid and one of the main problems that cause pathogens to resist newer generations beta-lactam antibiotics 12 , 13 , 14 . sul2 is the most common among enterobacteria that are associated with sulfonamides resistant.…”