Coexistence of Cavernous Hemangioma and Other Vascular Malformations of the Orbit

Strianese, Diego; Napoli, Manuela; Russo, Carmela; D'Errico, Arianna; Scotti, Nadia; Puoti, Gianfranco; Bonavolontà, Giulio; Tranfa, Fausto; Briganti, Francesco

doi:10.15274/nrj-2014-10016

Cited by 15 publications

(12 citation statements)

References 37 publications

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“…An OCVM is a venous malformation, also referred to as a cavernous vascular malformation (3,4). It is the most common type of orbital vascular malformation (5) and is sometimes present in combination with other vascular malformations (6).…”

Section: Introductionmentioning

confidence: 99%

Prognosis Analysis and Clinical Features of Orbital Cavernous Venous Malformations With Refractory Insidious Onset

Yang

Liu

et al. 2022

Front. Oncol.

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ObjectiveThe present study aims to analyse the clinical presentation, treatment and prognosis of a group of patients with orbital cavernous venous malformation (OCVM) with an insidious onset.MethodThe clinical data of 35 patients with OCVM treated at our centre between 2003 and 2020 were retrospectively analysed. The OCVMs were classified as one of six types (I–VI) according to the orbital position of the tumour. The clinical characteristics, treatment methods and follow-up results were recorded.ResultsA total of 35 patients with OCVM under the optic nerve sheath in the orbital apex area or the common tendon ring (Types I and II) were included in the present study. In 20 cases (57.1%), patients were misdiagnosed with optic neuritis, and in 20 cases (57.1%), the tumour was not identified based on imaging. The presentation was acute or subacute in 23 cases (65.7%). All patients underwent surgery: transnasal surgery in 22 cases (62.9%) and craniotomy in 13 cases (37.1%). A total of 9 patients (25.7%) experienced postoperative complications, and 17 patients (48.6%) experienced vision improvement. The average patient age at first diagnosis was 43.3 ± 10.3 years, and the median follow-up period was 64.5 months. Overall, 14 patients (40%) experienced postoperative complications: postoperative blindness in 6 cases, postoperative vision loss in 8 cases and orbital apex syndrome in 7 cases.ConclusionPatients with Type I and Type II OCVMs are the most complex cases. They have an insidious onset and are associated with a high rate of misdiagnosis and missed diagnosis. Acute and subacute decreases in visual acuity are mainly caused by OCVM haemorrhage. The difficulty of surgical treatment and the poor prognosis of postoperative vision are characteristics of this tumour. Transnasal surgery and craniotomy can be used to remove OCVMs located in the common tendon ring or optic canal as well as those involving the intracranial area through the supraorbital fissure. Meanwhile, the orbital approach (orbitotomy) has proven to be an effective method of treating OCVMs not involving the deep orbital apex and intracranial area.

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Section: Introductionmentioning

confidence: 99%

Prognosis Analysis and Clinical Features of Orbital Cavernous Venous Malformations With Refractory Insidious Onset

Yang

Liu

et al. 2022

Front. Oncol.

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“…The occurrence of multiple vascular anomalies in the same orbit has also been reported. Examples include VMs associated with varix, lymhangioma, and arteriovenous malformation [ 14 , 15 ]. Furthermore, VM and LM have been reported to occur together in other body parts including ulnar nerve and lymph nodes [ 16 , 17 ].…”

Section: Discussionmentioning

confidence: 99%

Ipsilateral Lymphatic and Venous Malformations Affecting the Midface Area

Bekdemir¹,

Gündüz

Ataoğlu

2020

Case Reports in Ophthalmological Medicine

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A 22-year-old woman presented with progressive swelling of the nasal conjunctiva in the left eye. Anterior segment examination revealed a diffuse cystic appearance to the inferonasal bulbar conjunctiva and plica semilunaris. Anterior segment swept-source optical coherence tomography (OCT) revealed clear hyporeflective spaces demarcated by hyperreflective septae in the affected conjunctiva, consistent with the diagnosis of lymphatic malformation (LM). Magnetic resonance imaging revealed a well circumscribed intraconal mass located inferonasally in the left orbit. Systemic examination revealed a lesion similar to LM on the left hard palate. The left conjunctival mass was excised subtotally. Subsequently, a transconjunctival anterior orbitotomy was performed and the left orbital mass was completely removed intact. Histopathologically, the conjunctival mass was diagnosed as LM and the orbital mass as venous malformation (VM). This case represents a rare coexistence of histopathologically proven conjunctival LM and orbital VM as well as a presumed LM of the hard palate, all 3 lesions occurring in the ipsilateral midface area.

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“…Bilateral cavernous haemangiomas can occur as a part of other systemic haemangiomatosis in Maffuci's syndrome and blue rubber bleb nevus syndrome 10 11. Rarely, unilateral multiple cavernous haemangioma of the orbit,12 coexistence of cavernous haemangioma with other vascular malformations, including orbital varices, lymphangioma and low-flow arteriovenous malformation,13 and association of orbital multifocal cavernous haemangioma with bilateral arachnoid cysts of the middle cranial fossa14 have been reported. In our case, owing to well-defined lesions in both orbits and based on the literature on coexistence of bilateral cavernous haemangioma with no significant personal history, a preoperative clinical diagnosis of bilateral cavernous haemangioma was made.…”

Section: Discussionmentioning

confidence: 99%

Concomitant orbital cavernous haemangioma and schwannoma in a patient

Gupta

Kaliki²,

Gowrishankar

2017

BMJ Case Reports

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A woman aged 39 years presented with right eye painless proptosis and decreased vision since 5 months. Right fundus examination revealed optic disc oedema. CT of the orbit revealed a well-defined homogeneous mass in the intraconal space in both orbits. Surgical excisional biopsy of the orbital lesions was performed. Histopathological examination of the right orbital lesion was suggestive of cavernous haemangioma and the left orbital lesion revealed schwannoma. The patient had an unremarkable postoperative course with improved visual acuity. This case illustrates benign orbital masses of 2 different tissues of origin in a single patient, which has not been described in the literature.

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Coexistence of Cavernous Hemangioma and Other Vascular Malformations of the Orbit

Abstract: SUMMARY -Coexistence of orbital cavernous hemangioma and other vascular malformations is unusual and few cases

Cited by 15 publications

References 37 publications

Prognosis Analysis and Clinical Features of Orbital Cavernous Venous Malformations With Refractory Insidious Onset

Prognosis Analysis and Clinical Features of Orbital Cavernous Venous Malformations With Refractory Insidious Onset

Ipsilateral Lymphatic and Venous Malformations Affecting the Midface Area

Concomitant orbital cavernous haemangioma and schwannoma in a patient

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