Coexistence of Graves’ Disease (Basedow’s Disease) and Ulcerative Colitis

Abstract

The coexistence of Graves' disease (GD), also known as Basedow's disease, and ulcerative colitis (UC) is uncommon although both conditions involve the autoimmune process. This report reviews the English-and Japanese-language literature on coexisting hyperthyroidism and UC, and discusses cases of concomitant GD and UC reported since 1980. Of the 16 cases of concomitant GD and UC that were identified, 10 were female (62.5%). In one case (6.3%), GD and UC were simultaneously diagnosed. In nine cases (56.3%) GD developed before UC and in six cases (37.5%) UC developed before GD. The time interval between the development of the primary and the concomitant disease was 0-20 years. Most cases of concomitant GD and UC were treated with pharmacotherapy and there were no deaths reported.

Autoimmune Thyroid Diseases Concomitant with Crohn’s Disease and Ulcerative Colitis

“…In this report, we performed a literature search and reviewed the cases of concomitant CD and autoimmune thyroid diseases (GD and HT), comparing our findings with our previous reports of concomitant cases of ulcerative colitis and GD [5].…”

“…In nine cases (56.3%) of GD developed before UC, and in one case (6.3%), the two diseases were simultaneously diagnosed. The diagnosis of the concomitant diseases happened between the ages of 18 (or 19)-61 years and the time interval between the diagnosis of the primary and the concomitant disease was 0-20 years [5].…”