In this study, we propose an adaptive transmission power aware cluster scheduling algorithm using multiple channels in a WPAN in the presence of WLAN interference. Results: The algorithm includes node identification, channel allocation, clustering and time scheduling. To evaluate the performance of the proposed algorithm, the performance metrics such as Bit error, Packet Error Rate (PER), Throughput, Average End-End Delay and Average Jitter is measured through Qualnet simulation. PER is calculated from bit error rate. The simulation results are compared with the conventional TDMA scheme. Conclusion/Recommendations: The measurement result shows that the proposed algorithm is effective in an IEEE 802.15.4 cluster-tree network in the presence of multiple IEEE 802.11 interferers.