Coexistence of optic disc drusen and idiopathic intracranial hypertension in a non-obese female

Venkataramana, Pradeep Addagadde; Patil, Preetham B; Koti, Shivabasappa V; Shetty, Varna

doi:10.4103/2320-3897.163298

Cited by 2 publications

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The link between PTCS and papilledema raises the question: does the presence of optic disc drusen rule out PTCS? Until recently, the coexistence of PTCS and optic nerve drusen was attested in only some case reports (12)(13)(14)(15)(16)(17). However, two larger studies suggest that PTCS and drusen are indeed found concurrently.…”

Section: Introductionmentioning

confidence: 99%

Optic Nerve Drusen Is Highly Prevalent Among Children With Pseudotumor Cerebri Syndrome

Genizi

Meiselles

Arnowitz³

et al. 2021

Front. Neurol.

View full text Add to dashboard Cite

Introduction: The clinical presentation of pseudotumor cerebri syndrome (PTCS) usually includes headache, nausea, and vomiting with normal physical examination apart from papilledema and diplopia. However, pseudopapilledema, which can be caused by optic nerve drusen, may lead to misdiagnosis. The prevalence of optic nerve drusen in the general population is 0.5–2%. The purpose of our study was to evaluate the prevalence and risk factors of optic nerve drusen among patients with PTCS.Materials and Methods: Medical records of children evaluated in the pediatric department at Bnai Zion Medical Center due to PTCS between 2008 and 2020 were assessed. Inclusion criteria were children age under 18 years with a PTCS diagnosis and ophthalmic B-mode ultrasonography (US). Exclusion criteria were secondary intracranial hypertension.Results: Thirty-four children were included with a mean age 10.1 years which included 50% boys. A majority of the patients, 24 (72.4%), complained of headaches, while 15 (45.5%) complained of transient visual obscuration, and 9 (26.5%) of vomiting. Visual acuity on presentation was normal (20/20–20/30) in 23 of the children (67%), moderately diminished (20/40–20/80) in 9 (26%), and showing profound loss (20/200) in 2 (7%). Five patients (14.7%) were diagnosed with optic nerve drusen via B-mode ophthalmic ultrasonography (US). However, they still fulfilled the diagnostic criteria for PTCS, and disc swelling improved after treatment. There were no statistically significant differences between the group with optic nerve drusen and the rest of the patients.Conclusions: Optic nerve drusen are common among pediatric patients with PTCS. Diagnosis of optic nerve drusen should not rule out the presence of increased intracranial pressure.

show abstract

Section: Introductionmentioning

confidence: 99%

Optic Nerve Drusen Is Highly Prevalent Among Children With Pseudotumor Cerebri Syndrome

Genizi

Meiselles

Arnowitz³

et al. 2021

Front. Neurol.

View full text Add to dashboard Cite

show abstract

“…1 Idiopathic Intracranial Hypertension (IIH) is a headache syndrome characterized by papilloedema with normal cerebrospinal fluid (CSF) composition and normal neuroimaging. 2,3 Pseudopapilledema is an apparent optic disc swelling secondary to a benign process such as buried Optic Nerve Head (ONH) drusen, hypoplastic, tilted or hyperopic disc. ONH drusen accounts for 75% of clinically diagnosed cases of pseudopapilledema.…”

Section: Introductionmentioning

confidence: 99%

Bilateral Buried Optic Nerve Head Drusen Mimicking Idiopathic Intracranial Hypertension

Sahu¹

2021

Delhi Journal of Ophthalmology

View full text Add to dashboard Cite

Optic nerve head (ONH) drusen are buried deposits in the optic nerve head simulating papilloedema. Idiopathic Intracranial Hypertension (IIH) signifies raised intracranial pressure in the absence of intracranial space occupying lesion. A 35-year old woman diagnosed elsewhere with IIH and treated with oral acetazolamide for six months, presented with non-specific headache. Fundus showed bilateral blurring of disc margins, elevated disc and obscuration of cup. MRI of brain was normal. The non-resolution of disc edema despite six months of acetazolamide therapy raised suspicion of an alternate diagnosis. Ultrasound B-scan confirmed the diagnosis of ONH drusen. ONH drusen should be excluded before entertaining the diagnosis of IIH.

show abstract

Coexistence of optic disc drusen and idiopathic intracranial hypertension in a non-obese female

Cited by 2 publications

References 0 publications

Optic Nerve Drusen Is Highly Prevalent Among Children With Pseudotumor Cerebri Syndrome

Optic Nerve Drusen Is Highly Prevalent Among Children With Pseudotumor Cerebri Syndrome

Bilateral Buried Optic Nerve Head Drusen Mimicking Idiopathic Intracranial Hypertension

Contact Info

Product

Resources

About