Coexistence of Two Epstein-Barr Virus–associated Malignancies: Lymphoepithelioma-like Cholangiocarcinoma in a Patient with a History of Undifferentiated Nasopharyngeal Carcinoma

Abstract

Undifferentiated nasopharyngeal carcinoma is particularly common in Southern China and is consistently associated with Epstein-Barr virus. In contrast, lymphoepithelioma-like carcinoma of the bile duct is a rare disease and not always associated with Epstein-Barr virus. We report the first case of coexisting Epstein-Barr virus-associated nasopharyngeal carcinoma and lymphoepithelioma-like carcinoma of the bile duct in aChinese patient. 中文摘要 兩種Epstein-Barr病毒相關惡性腫瘤並存：一名有未分化鼻咽癌病史的 病人併發淋巴上皮瘤樣膽管癌 戴燕萍、顏繼昌、丁信顯 未分化鼻咽癌在南中國地區特別常見，發病通常與Epstein-Barr病毒相關。相反，淋巴上皮瘤樣膽管 癌是一種罕見疾病，且不一定與Epstein-Barr病毒相關。本文報告首個併發Epstein-Barr病毒相關性鼻 咽癌和淋巴上皮瘤樣膽管癌的華籍病例。