Coexistencia de artritis séptica y microcristalina: un reto diagnóstico. A propósito de 25 casos

Prior-Español, Águeda; García-Mira, Yaiza; Mínguez, Sonia; Martínez-Morillo, Melania; Gifre, Laia; Mateo, Lourdes

doi:10.1016/j.reuma.2017.12.015

Cited by 9 publications

(1 citation statement)

References 17 publications

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“…It is very rare to see both acute gouty arthritis and septic arthritis co-exist in the same joint, and only a few cases have been reported in the first metatarsal phalangeal joint 13. One theory is that this is because gout is episodic in nature rather than being a long-standing chronic condition 14.…”

Section: Discussionmentioning

confidence: 99%

Citrobacter kosericausing osteomyelitis in a diabetic foot with concomitant acute gouty arthritis successfully treated with ertapenem

Tinevez

Knezevic²

2019

BMJ Case Rep

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We present an elderly diabetic man with left hallux pain and drainage who was initially diagnosed with acute gouty arthritis using the diagnostic rule for acute gout and monosodium urate crystals presented on synovial fluid analysis. Further investigation with surgical debridement, plain X-ray, MRI and wound culture revealed concomitant Citrobacter koseri septic arthritis with osteomyelitis. C. koseri is considered an opportunistic infection that rarely causes musculoskeletal infections. Acute gouty arthritis and septic arthritis are rarely seen occurring concomitantly in the same joint and are often difficult to differentiate due to similar findings on exam and imaging. The present case illustrates that osteomyelitis with an opportunistic organism can present concomitantly with acute gouty arthritis, and the diagnosis of one should not exclude the other.

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Section: Discussionmentioning

confidence: 99%

Citrobacter kosericausing osteomyelitis in a diabetic foot with concomitant acute gouty arthritis successfully treated with ertapenem

Tinevez

Knezevic²

2019

BMJ Case Rep

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Synovial fluid dual‐biomarker algorithm accurately differentiates osteoarthritis from inflammatory arthritis

Keter,

Thai‐Paquette,

Miamidian

et al. 2024

Journal Orthopaedic Research

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Osteoarthritis (OA) prevalence increases as the population ages. Diagnosing osteoarthritis often occurs in the late stages when cartilage degradation is severe, making it difficult to distinguish from other types of arthritis. Accurate differentiation of primary osteoarthritis from other arthritic conditions is crucial for effective treatment planning. A new diagnostic test has been developed that uses a dual‐biomarker algorithm to inform osteoarthritis diagnosis. Synovial fluid from patients with confirmed primary osteoarthritis showed elevated levels of cartilage oligomeric matrix protein. However, this biomarker alone could not distinguish primary osteoarthritis from other inflammatory conditions that also cause cartilage deterioration. Therefore, a combinatorial algorithm using cartilage oligomeric matrix protein and Interleukin‐8 concentrations was developed to differentiate primary osteoarthritis from inflammatory arthritis. Clinical decision limits for cartilage oligomeric matrix protein concentration and the cartilage oligomeric matrix protein to Interleukin‐8 ratio were established and validated using 171 human knee synovial fluid specimens. The osteoarthritis algorithm demonstrated clinical sensitivity and specificity of 87.0% and 88.9%, respectively. This is the first report of a biomarker test that can differentiate primary osteoarthritis from inflammatory arthritis with a high degree of accuracy.

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Broad-range 16 s rDNA PCR in synovial fluid does not improve the diagnostic performance of septic arthritis in native joints in adults: cross-sectional single-center study in 95 patients

et al. 2019

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Coexistencia de artritis séptica y microcristalina: un reto diagnóstico. A propósito de 25 casos

Cited by 9 publications

References 17 publications

Citrobacter kosericausing osteomyelitis in a diabetic foot with concomitant acute gouty arthritis successfully treated with ertapenem

Citrobacter kosericausing osteomyelitis in a diabetic foot with concomitant acute gouty arthritis successfully treated with ertapenem

Synovial fluid dual‐biomarker algorithm accurately differentiates osteoarthritis from inflammatory arthritis

Broad-range 16 s rDNA PCR in synovial fluid does not improve the diagnostic performance of septic arthritis in native joints in adults: cross-sectional single-center study in 95 patients

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