Coffee administration to promote return of bowel function after small bowel resection: A randomized, controlled trial

Holland, Conor; Shaffer, Lynn; Dobkin, Elliot; Hall, Jamie

doi:10.1016/j.amjsurg.2023.03.026

Cited by 4 publications

(2 citation statements)

References 25 publications

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“…Recent studies on coffee consumption after colorectal and gynecological surgeries have proven to reduce the gastrointestinal impairment. In a study conducted by Holland et al, post-operative coffee consumption was found to be safe and inexpensive and it reduced the length of hospital stay in patients having resection of their small intestines (intervention coffee group had a hospital stay of 6.7 median days and the group who was given only water post-operatively had a median hospital stay of 7.7 days) 14 .…”

Section: Resultsmentioning

confidence: 99%

Role Of Caffeine As A Bowel Stimulant After Major Gynecological Surgeries

Jabeen,

Yasmeen,

Riaz

et al. 2024

ashkmdc

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Objective: To investigate the role of caffeine as a bowel stimulant after major gynecological surger- ies. Coffee is a low-cost strategy to accelerate postoperative recovery of intestinal function/motility af- ter colorectal and gynecological surgery. Postoperative ileus or bowel paralysis is quite common in the postoperative period after abdominal surgery, such as elective colectomy, colorectal resection, caesarean section, or gynecological surgery. The occurrence of postoperative ileus leads to pro- longed patient hospital stay. Methods: This randomized control study was single-centered, conducted in Obstetrics and Gynecol- ogy department of Liaquat National Hospital Karachi after approval from Research and Ethical review committee of hospital (Ref#:0416-2019-LNH-ERC ). The duration of study was one year from 20th February2019 to 20th February 2020. In this randomized controlled trial, 120 patients were randomly assigned before major gynecological surgery into control and intervention groups. Results: A total of 120 women who met the inclusion and exclusion criteria were included in the study. Descriptive statistics of the demographic data were similar between the two groups. Statistical significant difference (p= 0.001) was found between the mean time (23±6.9 vs. 30±9.4 hours) for the passage of first flatus between the intervention group and the control group. Mean time to first bowel movement (37±6.8 vs. 30±4.8 hours), mean time to first defecation (42±8.3 vs.32±6.6 hours) and mean length of hospital stay after surgery (101±7.8 vs.72±5.6 hours) showed statistical significant difference between the two groups with p-value<0.05. Conclusion: Coffee consumption (caffeine) after major gynecological surgery played an important role as a bowel stimulant. Drinking coffee reduced the mean time for first passage of flatus, First bowel sound, first defecation, and hours of hospital stay after surgery.

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Section: Resultsmentioning

confidence: 99%

Role Of Caffeine As A Bowel Stimulant After Major Gynecological Surgeries

Jabeen,

Yasmeen,

Riaz

et al. 2024

ashkmdc

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“…Several components including caffeine, CGA (chlorogenic acid), melanoidins, and diterpenes, are associated with mucous secretion and gastrointestinal motor function [ 16 ]. Coffee consumption has been described to stimulate intestinal motility in healthy individuals [ 43 ] and after colorectal surgery [ 44 ] and small bowel resection [ 45 ]. The physiological effect of caffeine on intestinal activity is based on several mechanisms, including calcium-mediated vasodilation [ 46 ], vagus nerve stimulation [ 47 ], and gastrin release [ 48 ].…”

Section: Discussionmentioning

confidence: 99%

Caffeine intake enhances bowel recovery after colorectal surgery: a meta-analysis of randomized and non-randomized studies

Vaghiri,

Prassas,

David

et al. 2024

Updates Surg

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Postoperative ileus (POI) after colorectal surgery is a major problem that affects both patient recovery and hospital costs highlighting the importance of preventive strategies. Therefore, we aimed to perform a systematic analysis of the effects of postoperative caffeine consumption on bowel recovery and surgical morbidity after colorectal surgery. A comprehensive literature search was conducted through September 2023 for randomized and non-randomized trials comparing the effect of caffeinated versus non-caffeinated drinks on POI by evaluating bowel movement resumption, time to first flatus and solid food intake, and length of hospital stay (LOS). Secondary outcome analysis included postoperative morbidity in both groups. After data extraction and inclusion in a meta-analysis, odds ratios (ORs) for dichotomous variables and standardized mean differences (SMDs) for continuous outcomes with 95% confidence intervals (CIs) were calculated. Subgroup analyses were performed in cases of substantial heterogeneity. Six randomized and two non-randomized trials with a total of 610 patients were included in the meta-analysis. Caffeine intake significantly reduced time to first bowel movement [SMD −0.39, (95% CI −0.66 to −0.12), p = 0.005] and time to first solid food intake [SMD −0.41, (95% CI −0.79 to −0.04), p = 0.03] in elective laparoscopic colorectal surgery, while time to first flatus, LOS, and the secondary outcomes did not differ significantly. Postoperative caffeine consumption may be a reasonable strategy to prevent POI after elective colorectal surgery. However, larger randomized controlled trials (RCTs) with homogeneous study protocols, especially regarding the dosage form of caffeine and coffee, are needed.

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Coffee makes everything better … …

Cheng,

Kushnir

2023

The American Journal of Surgery

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Coffee administration to promote return of bowel function after small bowel resection: A randomized, controlled trial

Cited by 4 publications

References 25 publications

Role Of Caffeine As A Bowel Stimulant After Major Gynecological Surgeries

Role Of Caffeine As A Bowel Stimulant After Major Gynecological Surgeries

Caffeine intake enhances bowel recovery after colorectal surgery: a meta-analysis of randomized and non-randomized studies

Coffee makes everything better … …

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