Coffee and cancer: A prospective study of 43,000 Norwegian men and women

Stensvold, Inger; Jacobsen, Bjarne K.

doi:10.1007/bf01694753

Cited by 185 publications

(163 citation statements)

References 18 publications

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“…The majority of case-control studies of renal cell cancer have found no significant associations [9][10][11][12][13][14]16,17 for coffee consumption. Only a few prospective studies, 22,24,58,59 3 of which 22,24 (2 studies were reported in 1 paper; Lee et al…”

Section: Discussionmentioning

confidence: 99%

“…In the 2 cohort studies that were not included in our analysis because they did not meet the prespecified criteria (described in Material and Methods section), significant association in women and men combined 58 or non-significant inverse association in men 59 were found for coffee consumption. Our data suggested the inverse association was limited to women, although the difference in the risk estimates between women and men was not statistically significant.…”

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confidence: 99%

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Intakes of coffee, tea, milk, soda and juice and renal cell cancer in a pooled analysis of 13 prospective studies

Lee

Hunter

Spiegelman

et al. 2007

Intl Journal of Cancer

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Specific beverage intake may be associated with the risk of renal cell cancer through a diluting effect of carcinogens, alterations of hormone levels, or other changes in the renal tubular environment, but few prospective studies have examined these associations. We evaluated the associations between coffee, tea, milk, soda and fruit and vegetable juice intakes and renal cell cancer risk in a pooled analysis of 13 prospective studies (530,469 women and 244,483 men). Participants completed a validated foodfrequency questionnaire at baseline. Using the primary data, the study-specific relative risks (RRs) were calculated and then pooled using a random effects model. A total of 1,478 incident renal cell cancer cases were identified during a follow-up of 7-20 years across studies. Coffee consumption was associated with a modestly lower risk of renal cell cancer (pooled multivariate RR for 3 or more 8 oz (237 ml) cups/day versus less than one 8 oz (237 ml) cup/day 5 0.84; 95% CI 5 0.67-1.05; p value, test for trend 5 0.22). Tea consumption was also inversely associated with renal cell cancer risk (pooled multivariate RR for 1 or more 8 oz (237 ml) cups/day versus nondrinkers 5 0.85; 95% CI 5 0.71-1.02; p value, test for trend 5 0.04). No clear associations were observed for milk, soda or juice. Our findings provide strong evidence that neither coffee nor tea consumption increases renal cell cancer risk. Instead, greater consumption of coffee and tea may be associated with a lower risk of renal cell cancer. ' 2007 Wiley-Liss, Inc.

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Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

Intakes of coffee, tea, milk, soda and juice and renal cell cancer in a pooled analysis of 13 prospective studies

Lee

Hunter

Spiegelman

et al. 2007

Intl Journal of Cancer

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“…[27][28][29][30][31][32][33][34][35][36] Among them, 1 argued an increasing risk, 27 3 suggested an inverse association, 29,34,36 and 6 observed no association. 28,[30][31][32][33]35 Our study was consistent with the latter 6 studies.…”

Section: Discussionmentioning

confidence: 99%

Coffee consumption and the risk of colorectal cancer: A prospective cohort study in Japan

Naganuma

Kuriyama

Akhter

et al. 2007

Intl Journal of Cancer

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An inverse association between coffee consumption and the risk of colorectal cancer has been reported in several case-control studies, but results from prospective cohort studies have been inconclusive. We conducted a prospective cohort study among a Japanese population to clarify the association between coffee consumption and the risk of colorectal cancer incidence. We used data from the Miyagi Cohort Study for this analysis. Usable self-administered questionnaires about coffee consumption were returned from 22,836 men and 24,769 women, aged 40-64 years, with no previous history of cancer. We used the Cox proportional-hazard regression model to estimate hazard ratios and 95% confidence intervals. During 11.6 years of follow-up (425,303 person-years), we identified 457 cases of colorectal cancer. Coffee consumption was not associated with the incidence of colorectal, colon or rectal cancer. The multivariate-adjusted hazard ratio (95% confidence interval) of colorectal cancer incidence for 3 or more cups of coffee per day as compared with no consumption was 0.95 (0.65-1.39) for men and women (p for trend 5 0.55), 0.91 (0.56-1.46) for men (p for trend 5 0.53) and 1.16 (0.60-2.23) for women (p for trend 5 0.996). Coffee consumption was also not associated with incidence of either proximal or distal colon cancer. We conclude that coffee consumption is not associated with the incidence risk of colorectal cancer in the general population in Japan. ' 2006 Wiley-Liss, Inc.Key words: coffee; colorectal cancer; incidence; Japan; prospective study Colorectal cancer is one of the most common cancers worldwide. 1,2 In Japan, colorectal cancer ranks second in terms of agestandardized incidence rate among all cancers, and it is increasing rapidly. 3 Therefore, primary prevention of colorectal cancer worldwide, including Japan, is a considerable public health concern.Coffee is considered to be a protective factor against colorectal cancer through activity of its anticarcinogenic constituents, cafestol and kahweol. 4 It may also decrease the risk of colorectal cancer by reducing the excretion of bile acids and neutral sterols into the colon. 5 Some epidemiological studies have examined the relationship between coffee consumption and the risk of colorectal cancer. 6 Sixteen out of 20 case-control studies supported an inverse association between high coffee consumption and colorectal cancer risk. [7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26] However, the results of those studies may have been affected by selection bias or recall bias due to retrospective assessment of coffee consumption and other lifestyles-related factors after diagnosis of cancer. In contrast, results from prospective cohort studies have been inconclusive. [27][28][29][30][31][32][33][34][35][36] Among 10 such studies, 1 suggested an increasing risk, 27 3 showed an inverse association 29,34,36 and the others observed no association. 28,[30][31][32][33]35 However, as the studies that observed any association had some statistical l...

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“…To assess a summary OR/RR for colorectal cancer in both sexes, we used combined estimates if provided. Otherwise, we included all estimates according to sex and/or cancer site in the analysis as if obtained from different studies (11,19,20,22,25,27,(30)(31)(32)(33)(34)(35)(36)(37)(38) . Some studies reported estimates for caffeinated coffee, decaffeinated coffee and/or caffeine; we chose the first one (11,15,31,34,36a,36b) .…”

Section: Inclusion Criteriamentioning

confidence: 99%

Coffee consumption and risk of colorectal cancer: a meta-analysis of observational studies

Ma²,

Zhang³

et al. 2012

Public Health Nutr.

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Objective: Separate meta-analyses based on case-control and cohort studies have reported different results on the relationship between coffee consumption and colorectal cancer risk. To clarify the effect of coffee intake on colorectal cancer risk, we performed a meta-analysis based on both case-control and cohort studies. Design: Review study. Setting: We identified case-control and cohort studies related to coffee consumption and colorectal cancer risk listed on MEDLINE, the Cochrane Controlled Trials Register, EMBASE, Science Citation Index and PubMed (until May 2011). In subgroup analyses using case-control studies, significant inverse associations were found in females for colorectal cancer and in Europe for colorectal and colon cancer, while the subgroup analyses of cohort studies found that coffee drinks substantially decreased risk of colon cancer only in Asian women. Conclusions: Results from case-control studies suggest coffee consumption can significantly decrease the risks of colorectal cancer and colon cancer, especially in Europe and for females. Keywords Colorectal cancer Coffee Meta-analysis Observational studiesColorectal cancer is the third most common cancer in men and the second most common in women worldwide, with over 1?2 million new cancer cases and 608 700 deaths occurring in 2008 (1) . It is well known that obesity, smoking and physical inactivity are important risk factors for colorectal cancer. However, nutritional factors such as alcohol, tea, coffee, etc. have also been considered to play an important role in the development of colorectal cancer (2) .Coffee is a complex mixture of more than a thousand chemicals, and these constituents have potential genotoxic and mutagenic properties, antioxidant and antimutagenic activities to affect colorectal cancer risk (3) . Over the last four decades, the relationship between coffee consumption and colorectal cancer risk has been extensively examined (4) . In 1990, a Working Group of the International Agency for Research on Cancer reviewed the data on coffee consumption and colorectal cancer risk and concluded that in man 'there is some evidence of an inverse relation between coffee drinking and cancer of the large bowel' (3) . However, the relationship between coffee intake and colorectal cancer risk appears inconsistent in case-control studies and cohort studies. To clarify the relationship between coffee consumption and colorectal cancer risk, Giovannucci performed a meta-analysis in 1998 and reported an overall OR/relative ratio (RR) for high v. low coffee intake of 0?72 (95 % CI 0?61, 0?84) and 0?97 (95 % CI 0?73, 1?29) after combining the results of twelve case-control studies and five cohort studies, respectively (5) . A subsequent meta-analysis (6) and a pooled analysis (7) for cohort studies showed no significant inverse associations; however, another meta-analysis in 2011 *Corresponding authors: Email

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Coffee and cancer: A prospective study of 43,000 Norwegian men and women

Cited by 185 publications

References 18 publications

Intakes of coffee, tea, milk, soda and juice and renal cell cancer in a pooled analysis of 13 prospective studies

Intakes of coffee, tea, milk, soda and juice and renal cell cancer in a pooled analysis of 13 prospective studies

Coffee consumption and the risk of colorectal cancer: A prospective cohort study in Japan

Coffee consumption and risk of colorectal cancer: a meta-analysis of observational studies

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