1970
DOI: 10.1136/thx.25.4.399
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Coffee worker's lung: A new example of extrinsic allergic alveolitis

Abstract: A man who worked for more than 20 years in a coffee-roasting factory developed lung lesions. By immunol-ogical investigations it was proven that there were circulating antibodies against coffee-bean dust in the patient's serum. Immunofluorescence of the lung biopsy demonstrated deposits of IgG and complement along the alveolar capillaries. The histological features are described.

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Cited by 46 publications
(10 citation statements)
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“…Hence it seems that there is a baseline level of factory air dust in the order of 1*0 mg/i3 or less, comprised of small circular particles of approximate diameter 5 ,u whose origin is not clear. With increasing factory activity, such as the operation of husking machines or sorting machines or the filling of sacks, dust levels rise to up to 10 times this basic level, and 40-85% of this dust is comprised of large particles.…”
Section: Samplingmentioning
confidence: 99%
See 1 more Smart Citation
“…Hence it seems that there is a baseline level of factory air dust in the order of 1*0 mg/i3 or less, comprised of small circular particles of approximate diameter 5 ,u whose origin is not clear. With increasing factory activity, such as the operation of husking machines or sorting machines or the filling of sacks, dust levels rise to up to 10 times this basic level, and 40-85% of this dust is comprised of large particles.…”
Section: Samplingmentioning
confidence: 99%
“…There have been many published accounts of allergy to coffee beans in those occupationally exposed. Asthma,24 extrinsic allergic alveolitis,5 dermatitis,6 oedema,3 and rhinitis and lacrimation3 5 Gravimetric assays of dust levels were made in one coffee factory using a Sartorius MB2 air sampler with 5-0 A Millipore SM filters. Assays were made on 11 different days over a six week period when the level of activity in the factory varied considerably from day to day depending principally on the quantity of coffee beans available for processing.…”
mentioning
confidence: 99%
“…Rhinitis, asthma, conjunctivitis, or dyspnoea in subjects exposed to coffee have been reported by several authors.2-3 However, there have been few studies dealing with the more detailed immunological changes related to coffee dust exposure. [6][7][8][9][10] In the present epidemiological investigation we have studied the relationship between some immunological tests and lung function changes.…”
mentioning
confidence: 99%
“…The results in 11 cases were compared with those obtained by immunofluorescence using frozen sections. Tissue was obtained from surgical specimens of cases with interstitial pneumonia comprising 10 of the usual type (UIP) and three of the desquamative type (DIP).…”
mentioning
confidence: 99%