Cognitive and behavioral factors associated to probable sarcopenia in community-dwelling older adults

Souza, Larissa Franciny de; Fontanela, Laís Coan; Gonçalves, Camila Teles; Mendrano, Amanda Lena; Freitas, Mariana Alves; Danielewicz, Ana Lúcia; Avelar, Núbia Carelli Pereira de

doi:10.1080/0361073x.2021.1939564

Cited by 10 publications

(26 citation statements)

References 60 publications

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“…All participants were visited at home and answered a questionnaire with information about their medical history, life habits, and comorbidities. The exclusion criteria were age (<65), cognitive decline evaluated by the Mini Mental State Examination [ 3 ], subjects unable to walk independently, hospitalized or had suffered fractures in the last three months, presence of neoplasm in the last five years, in palliative care, subjects that performed physical activity on a regular basis (more than three times a week), and subjects with severe visual and auditory impairment and with acute cardiorespiratory diseases.…”

Section: Methodsmentioning

confidence: 99%

“…Low muscle mass and function may result in a reduced quality of life, a loss of independence, a need for long-term care, an increased risk of falls and fractures, and mortality [ 1 , 2 ]. Cognitive impairment, fear of falling, depressive symptoms, a poor or fair self-perception of health, and inflammation are a few of the characteristics that might predispose a person to sarcopenia [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

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Adiponectin Is a Contributing Factor of Low Appendicular Lean Mass in Older Community-Dwelling Women: A Cross-Sectional Study

Teixeira

Santos

Parentoni

et al. 2022

JCM

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Inflammation is a chronic, sterile, low-grade inflammation that develops with advanced age in the absence of overt infection and may contribute to the pathophysiology of sarcopenia, a progressive and generalized skeletal muscle disorder. Furthermore, a series of biomarkers linked to sarcopenia occurrence have emerged. To aid diagnostic and treatment strategies for low muscle mass in sarcopenia and other related conditions, the objective of this work was to investigate potential biomarkers associated with appendicular lean mass in community-dwelling older women. This is a cross-sectional study with 71 older women (75 ± 7 years). Dual-energy X-ray absorptiometry was used to assess body composition. Plasmatic blood levels of adipokines (i.e., adiponectin, leptin, and resistin), tumor necrosis factor (TNF) and soluble receptors (sTNFr1 and sTNFr2), interferon (INF), brain-derived neurotrophic factor (BDNF), and interleukins (IL-2, IL-4, IL-5, IL-6, IL-8, and IL-10) were determined by enzyme-linked immunosorbent assay. Older women with low muscle mass showed higher plasma levels of adiponectin, sTNFr1, and IL-8 compared to the regular muscle mass group. In addition, higher adiponectin plasma levels explained 14% of the lower appendicular lean mass. High adiponectin plasmatic blood levels can contribute to lower appendicular lean mass in older, community-dwelling women.

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Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Adiponectin Is a Contributing Factor of Low Appendicular Lean Mass in Older Community-Dwelling Women: A Cross-Sectional Study

Teixeira

Santos

Parentoni

et al. 2022

JCM

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“…Other authors also found high prevalence rates in their sample when using this functional test. For example, de Souza et al (2022) found a prevalence of probable sarcopenia of 64.1% for older women from the city of Balneário Arroio do Silva in the state of Santa Catarina, Brazil [31]. Another study conducted by de Souza et al (2022) observed a prevalence of probable sarcopenia of 42.0% in older Brazilian women using data from a study with probabilistic sampling carried out in Florianópolis in the state of Santa Catarina, Brazil [32].…”

Section: Discussionmentioning

confidence: 99%

Prevalence of sarcopenia in older women and level of agreement between the diagnostic instruments proposed by the European Working Group on Sarcopenia in Older People 2 (EWGSOP2)

Sutil

Parentoni

Teixeira

et al. 2023

BMC Musculoskelet Disord

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Background The European Working Group on Sarcopenia in Older People 2 (EWGSOP2) proposed the use of different diagnostic tools to assess sarcopenia. This study aimed to determine prevalence rates of sarcopenia according to the diagnostic instruments proposed by EWGSOP2 and to assess their level of agreement in older Brazilian women. Methods A cross-sectional study with 161 community-dwelling older Brazilian women. Probable sarcopenia was assessed through Handgrip Strength (HGS) and the 5-times sit-to-stand test (5XSST). In addition to reduced strength, Appendicular Skeletal Muscle Mass (ASM) (obtained by Dual-energy X-ray absorptiometry) and ASM/height² were considered for diagnosis confirmation. Sarcopenia severity was determined by reduced muscle strength and mass and poor functional performance assessed by Gait Speed (GS), Short Physical Performance Battery (SPPB), and Timed Up and Go test (TUG). McNemar’s test and Cochran’s Q-test were used to compare sarcopenia prevalence. Cohen’s Kappa and Fleiss’s Kappa tests were used to assess the level of agreement. Results The prevalence of probable sarcopenia was significantly different (p < 0.05) when using HGS (12.8%) and 5XSST (40.6%). Regarding confirmed sarcopenia, the prevalence was lower when using ASM/height² than with ASM. Regarding severity, the use of SPPB resulted in a higher prevalence in relation to GS and TUG. Conclusion There were differences in the prevalence rates of sarcopenia and low agreement between the diagnostic instruments proposed by the EWGSOP2. The findings suggest that these issues must be considered in the discussion on the concept and assessment of sarcopenia, which could ultimately help to better identify patients with this disease in different populations.

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“…2 Age-related loss of strength and muscle mass, or sarcopenia, negatively affects mobility, increasing the risk of depression, falls, and diminished quality of life. 3 When older adults are hospitalized, their mobility is often abruptly restricted, leading to rapid functional decline. 4,5 The focus on reducing falls in hospitals-owing to the Centers for Medicare and Medicaid Services no longer reimbursing for fall-related costs-has had the unintended consequence of limiting mobility, thereby causing associated adverse outcomes like delirium and pressure injuries.…”

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confidence: 99%

Promoting Safe Mobility Strategies for partnering with caregivers to maximize older adults' functional ability.

Olson

Zonsius

Rodriguez-Morales

et al. 2023

Home Healthcare Now

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This article is the fifth in a series, Supporting Family Caregivers in the 4Ms of an Age-Friendly Health System, published in collaboration with the AARP Public Policy Institute as part of the ongoing Supporting Family Caregivers: No Longer Home Alone series. The 4Ms of an Age-Friendly Health System (What Matters, Medication, Mentation, and Mobility) is an evidence-based framework for assessing and acting on critical issues in the care of older adults across settings and transitions of care. Engaging the health care team, including older adults and their family caregivers, with the 4Ms framework can help to ensure that every older adult gets the best care possible, is not harmed by health care, and is satisfied with the care they receive. The articles in this series present considerations for implementing the 4Ms framework in the inpatient hospital setting and incorporating family caregivers in doing so. Resources for both nurses and family caregivers, including a series of accompanying videos developed by AARP and the Rush Center for Excellence in Aging and funded by The John A. Hartford Foundation, are also provided. Nurses should read the articles first, so they understand how best to help family caregivers. Then they can refer caregivers to the informational tear sheet—Information for Family Caregivers—and instructional videos, encouraging them to ask questions. For additional information, see Resources for Nurses. Cite this article as: Olson,L.M., et al. Promote Safe Mobility. Am J Nurs 2022; 122(7): 46-52.

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Cognitive and behavioral factors associated to probable sarcopenia in community-dwelling older adults

Cited by 10 publications

References 60 publications

Adiponectin Is a Contributing Factor of Low Appendicular Lean Mass in Older Community-Dwelling Women: A Cross-Sectional Study

Adiponectin Is a Contributing Factor of Low Appendicular Lean Mass in Older Community-Dwelling Women: A Cross-Sectional Study

Prevalence of sarcopenia in older women and level of agreement between the diagnostic instruments proposed by the European Working Group on Sarcopenia in Older People 2 (EWGSOP2)

Promoting Safe Mobility Strategies for partnering with caregivers to maximize older adults' functional ability.

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