Cognitive and brain morphological deviations in middle-to-old aged autistic adults: A systematic review and meta-analysis

Wang, Jingying; Christensen, Danielle; Coombes, Stephen A.; Wang, Zheng

doi:10.1016/j.neubiorev.2024.105782

Neuroscience & Biobehavioral Reviews

2024

DOI: 10.1016/j.neubiorev.2024.105782

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Cognitive and brain morphological deviations in middle-to-old aged autistic adults: A systematic review and meta-analysis

Jingying Wang,

Danielle Christensen,

Stephen A. Coombes

et al.

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Psychiatric Disease as a Potential Risk Factor for Dementia: A Narrative Review

Hedges,

Chase,

Farrer

et al. 2024

Brain Sciences

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Neurodegenerative disease is a major global health problem with 150 million people predicted to have dementia by 2050. Genetic factors, environmental factors, demographics, and some diseases have been associated with dementia. In addition to associations between diseases such as hypertension and cerebrovascular disease and dementia, emerging findings associate some psychiatric disorders with incident dementia. Because of the high and increasing global prevalence of dementia and the high worldwide prevalence of psychiatric disorders, the primary objective of this narrative review was to evaluate published findings that evaluate the association between bipolar disorder, depression, anxiety, post-traumatic stress disorder, obsessive–compulsive disorder, attention-deficit/hyperactivity disorder, autism spectrum disorder, schizophrenia and other psychosis syndromes, and personality disorders and personality traits and incident dementia. Here, we highlight findings indicating possible associations between these psychiatric disorders and subsequent dementia and suggest that some psychiatric disorders may be risk factors for incident dementia. Further research, including more large longitudinal studies and additional meta-analyses, however, is needed to better characterize the associations between psychiatric disorders and incident dementia, to identify possible mechanisms for these putative associations, and to identify risk factors within psychiatric disorders that predispose some people with a psychiatric disorder but not others to subsequent dementia. Additional important questions concern how the treatment of psychiatric disorders might affect the risk of incident dementia.

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Psychiatric Disease as a Potential Risk Factor for Dementia: A Narrative Review

Hedges,

Chase,

Farrer

et al. 2024

Brain Sciences

View full text Add to dashboard Cite

show abstract

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Cognitive and brain morphological deviations in middle-to-old aged autistic adults: A systematic review and meta-analysis

Cited by 1 publication

References 155 publications

Psychiatric Disease as a Potential Risk Factor for Dementia: A Narrative Review

Psychiatric Disease as a Potential Risk Factor for Dementia: A Narrative Review

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