Objective: To verify the effect of a cognitive and motor stimulation program on self-care, quality of life, depression, functional capacity and cognition of patients with chronic heart failure. Methodology: This is a quasi-experimental study of the type before and after, with a sample of 21 patients from a clinic specialized in the treatment of heart failure located in the state of Rio de Janeiro. The patients received the intervention of cognitive and motor stimulation, through a weekly program, with eight sessions of 90 minutes that consisted of cooperative, pedagogical games, group dynamics and circular dance. The assessed outcomes were self-care skills, quality of life, depression, activities of daily living and cognition. Statistical analysis occurred through the analysis of frequencies, mean, median. Parametric (Paired T-Student) and nonparametric (Wilcoxon) tests were used considering the bivariate p value <0.05. The final sample consisted of 21 patients, with a mean age of 67.92 ± 11.48. Result: Although the primary self-care outcome did not improve (p = 0.175), the pre- and post-intervention data showed significant improvements in the outcomes cognition (p≤0.05), quality of life (p≤0.05) and depression (p≤0.05) showing a significant effect of the intervention. Conclusion: Participants evolved positively in the outcomes cognition, depression and quality of life. Self-care outcomes and activities of daily living did not have statistical significance in their scores. Evidencing the importance of conducting new studies and deepening research in the field of cognition and HF.