Cognitive-Based Interventions to Improve Mobility: A Systematic Review and Meta-analysis

Marušič, Uroš; Verghese, Joe; Mahoney, Jeannette R.

doi:10.1016/j.jamda.2018.02.002

Cited by 75 publications

(69 citation statements)

References 39 publications

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“…A single‐blind randomized controlled trial with 5 years of follow‐up showed that reasoning training (a type of cognitive training) could slow functional decline in self‐reported instrumental activities of daily life . A meta‐analysis showed that cognitive training interventions could improve function‐related outcomes, especially physical function requiring higher‐order executive functions . The mechanisms underlying the relationship between cognitive function and functional limitation are not clear.…”

Section: Discussionmentioning

confidence: 99%

“…42 A meta-analysis showed that cognitive training interventions could improve function-related outcomes, especially physical function requiring higher-order executive functions. 43 The mechanisms underlying the relationship between cognitive function and functional limitation are not clear. At the simplest level, execution of the physical task involves the sensorimotor nervous system and requires information processing and attention.…”

Section: Discussionmentioning

confidence: 99%

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Weak Grip Strength and Cognition Predict Functional Limitation in Older Europeans

Wang

et al. 2018

J American Geriatrics Society

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Objectives To estimate the effects of baseline grip strength and cognition on the trajectory of functional limitation over time. Design Longitudinal study of older adults participating in the Survey of Health, Ageing and Retirement in Europe (SHARE). Setting Urban and rural households in 11 European countries and Israel. Participants Individuals aged 50 and older from SHARE (2004–2015) (N=14,073; 52.5% female). Measurements Outcomes were functional limitation scores from five panel wave. Main exposure variables were grip strength and cognitive measures including memory, verbal fluency, and numeracy at baseline. Basic demographic characteristics, life habits, and health status were considered as potential confounders. Mixed‐effect linear regression models were fitted. Results Functional limitation increased significantly over time (follow‐up range 0.9–11.6 years) (β = 0.051, P < .001). Mixed‐effect linear regression models identified significant interactions between grip strength (β = −0.001, P < .001), numeracy (β = −0.012, P < .001), verbal fluency (β = −0.003, P < .001), word recall (β = −0.006, P < .001) and time on functional limitation. Conclusion Stronger baseline grip strength and better cognition predicted a slower rate of increase in functional limitation over time in older adults. Grip strength and cognitive function appeared to be useful indicators of the functional limitation process and attested to their value in monitoring functional change in European older adults. J Am Geriatr Soc 67:93–99, 2019.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Weak Grip Strength and Cognition Predict Functional Limitation in Older Europeans

Wang

et al. 2018

J American Geriatrics Society

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“… 14 , 15 ) Pilot intervention trials to enhance EF either by cognitive training or brain stimulation have shown improvements in gait velocity. 16 , 17 )…”

Section: Gait Speed and Cognitive Decline In Generalmentioning

confidence: 99%

Motoric Cognitive Risk Syndrome: A Risk Factor for Cognitive Impairment and Dementia in Different Populations

Meiner

Ayers

Verghese

2020

Ann Geriatr Med Res

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Changes in gait, especially decreased gait velocity, may be a harbinger of cognitive decline in aging. Motoric cognitive risk syndrome (MCR), a pre-dementia syndrome combining slow gait and cognitive complaints, is a powerful clinical tool used to identify older adults at a high risk of developing dementia. The mean prevalence of MCR worldwide, including in a Korean cohort, was around 10%. The reported risk factors for incident MCR include older age, low education, cardiovascular disease, obesity, physical inactivity, and depression. In addition to dementia, MCR is also a risk factor for other age-related adverse conditions such as falls, disability, frailty, and mortality. The use of MCR has advantages over other pre-dementia syndromes in being much simpler to implement and requires fewer resources. Identification of mechanisms responsible for MCR may help in developing interventions to reduce the growing burden of dementia and disability worldwide.

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“…Alternatively, these individuals could be included in interventions with the aim of FRIENDSHIPS AND LONELINESS IN OLDER ADULTS 29 improving the other contributing factors to loneliness and psychological well-being such as health status and mobility (Theeke, 2009). These could include cognitive based interventions to improve mobility (Marusic, Verghese, & Mahoney, 2018) and physical activity interventions to improve mobility (Yeom, Keller, & Fleury, 2009) and health status (Hwang & Braun, 2015). As well as directly targeting psychological well-being with the aim of reducing loneliness in tandem.…”

Section: Discussionmentioning

confidence: 99%

Friendships, loneliness and psychological well-being in older adults: A limit to the benefit of the number friendships.

Thompson¹,

Ma²,

McNeill³

et al. 2020

Preprint

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Objectives: To examine the relationship between number of friends and loneliness, depression, anxiety and stress in older adults. Methods: Data were obtained from 335 older adults via completion of an online survey. Measures included loneliness (UCLA Version 3), depression, stress and anxiety (DASS-21). Participants also reported their number of close friends. Results: Regression analysis revealed a negative curvilinear relationship between number of friends and each of the measures tested. Breakpoint analysis demonstrated a threshold for the effect of number of friends on each of the measures (loneliness = 4, depression = 2, anxiety = 3, stress = 2). Discussion: The results suggest that there is a limit to the benefit of increasing the number of friends in older adults for each of these measures. Elucidating these thresholds can enable loneliness and psychological well-being interventions to be more targeted.

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Cognitive-Based Interventions to Improve Mobility: A Systematic Review and Meta-analysis

Cited by 75 publications

References 39 publications

Weak Grip Strength and Cognition Predict Functional Limitation in Older Europeans

Weak Grip Strength and Cognition Predict Functional Limitation in Older Europeans

Motoric Cognitive Risk Syndrome: A Risk Factor for Cognitive Impairment and Dementia in Different Populations

Friendships, loneliness and psychological well-being in older adults: A limit to the benefit of the number friendships.

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