Cognitive Behavior Therapy, Exercise, or Both for Treating Chronic Widespread Pain

Abstract

clinicaltrials.gov Identifier: ISRCTN67013851.

Economic evaluation alongside factorial trials: a systematic review of empirical studies

“…These are costeffectiveness analysis (CEA) and cost-utility analysis (CUA) ( Table 2). CEA was undertaken in six studies, [13,17,19,23,26,27] whereas CUA was undertaken in nine studies, [14][15][16][20][21][22]24,25,28] with one study undertaking both cost-consequence and cost-utility analysis [18]. All studies gave a justification of why they employed each economic evaluation technique and it was found to be appropriate to the research objectives.…”

'I just wanted someone to tell me it wasn't all in my mind and do something for me': Qualitative exploration of acceptability of a CBT based intervention to manage chronic orofacial pain

“…The resulting intervention consisted of a manual and a facilitator and was entitled "Managing Chronic Orofacial Pain". An existing manual for the management of chronic widespread pain (11), which produced evidence of positive effects for patients, was adapted for use with COFP patients. Two researchers (dentist and psychologist) were trained as facilitators for the intervention and supervised by an experienced CBT therapist.…”

Treatment expectations but not preference affect outcome in a trial of CBT and exercise for pain

“…The exercise program was conducted at a leisure facility gym and was led by a fitness instructor with whom participants could meet once a month. 8 A screening survey of patients registered at selected doctors’ practices in two areas of the UK, with approximately 15 000 respondents, was used to identify and recruit 442 participants. Eligible participants reported CWP (according to the definition in the American College of Rheumatology criteria for fibromyalgia) 10 for which they had consulted their general practitioner.…”

“…Participants were at least 25 years old, and exclusion criteria included contraindications to exercise and psychiatric disorder. 8 Confirmation of eligibility for the study and treatment allocation was conducted at clinic visits with a research nurse. The study received full ethical approval from the Cheshire Research Ethics Committee (reference number: 07/Q1506/61), the trial registration number was ISRCTN67013851, and all participants gave informed consent.…”

“…Then it is possible to see whether outcomes differ according to whether or not participants received their preferred treatment and whether or not they had high expectations for the treatment they received. The MUSICIAN Study is one such randomized trial that has previously reported effective treatments for pain 7,8 and that collected information on preference and expectations. The aim of the current analysis was to see whether patient-reported improvement in health (the main outcome) in a randomized trial for cognitive–behavioral therapy (CBT), exercise, or both treatments for patients with chronic widespread pain (CWP) was associated with nonspecific factors of treatment, namely, whether participants received the treatment they preferred and whether they expected improvement for the treatment they received.…”