2015
DOI: 10.1159/000381957
|View full text |Cite
|
Sign up to set email alerts
|

Cognitive Behavioral Analysis System of Psychotherapy versus Escitalopram in Chronic Major Depression

Abstract: Background: A specific psychotherapy for chronic depression, the Cognitive Behavioral Analysis System of Psychotherapy (CBASP), was compared to escitalopram (ESC). Methods: Sixty patients with chronic major depression were randomized to ‘CBASP' (22 sessions) or ‘ESC plus clinical management' (ESC/CM) at two treatment sites. The primary outcome measure was the score on the Montgomery-Asberg Depression Rating Scale (MADRS) after 8 weeks of acute treatment assessed by blinded raters. In the case of nonimprovement… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
2
1

Citation Types

0
41
0
1

Year Published

2016
2016
2018
2018

Publication Types

Select...
7
1

Relationship

3
5

Authors

Journals

citations
Cited by 49 publications
(42 citation statements)
references
References 50 publications
0
41
0
1
Order By: Relevance
“…The sustained remission rates are impressive, though. Results of this study together with results of other discussed studies [28] suggest that creative augmentation of antidepressants or psychotherapy with various therapeutic modalities (psychotherapy, chronotherapeutics, other medications) is a way to go in treating patients with treatment-resistant depression. (No funding for this study is declared, authors claim no conflict of interest.…”
Section: Issues In the Management Of Depressionmentioning
confidence: 62%
See 1 more Smart Citation
“…The sustained remission rates are impressive, though. Results of this study together with results of other discussed studies [28] suggest that creative augmentation of antidepressants or psychotherapy with various therapeutic modalities (psychotherapy, chronotherapeutics, other medications) is a way to go in treating patients with treatment-resistant depression. (No funding for this study is declared, authors claim no conflict of interest.…”
Section: Issues In the Management Of Depressionmentioning
confidence: 62%
“…Schramm et al [28] compared Cognitive Behavioral Analysis System of Psychotherapy (CBASP) to escitalopram (plus clinical management) in patients with chronic major depression at two university clinics in Germany. CBASP is a highly structured interpersonal learning approach integrating behavioral, cognitive, and mainly interpersonal treatment strategies.…”
Section: Issues In the Management Of Depressionmentioning
confidence: 99%
“…Models were based on 3 time points (baseline, midtreatment, posttreatment). As in previous research [39], models for the primary outcome were adjusted for depressive symptom severity from initial screening which are not influenced by specific treatment expectations (i.e., BDI scores when inclusion criteria were examined). Data from all 173 randomized participants were analyzed (for study flow, see Fig.…”
Section: Methodsmentioning
confidence: 99%
“…The primary objective of this naturalistic follow-up (German Clinical Trials Register: DRKS00008935) to the randomized clinical trial by Schramm et al [7] was a direct comparison of the long-term sustainability of CBASP versus escitalopram plus clinical management (ESC). Both treatments proved equally effective during an acute treatment phase of 8 weeks (12 sessions of CBASP) and 20 additional weeks of extended treatment (10 bi-weekly sessions of CBASP).…”
Section: Tablementioning
confidence: 99%
“…Methodological details are published elsewhere [7]. The primary outcome measure was depression symptoms measured by the Inventory of Depressive Symptomatology (IDS-SR); the secondary outcome measure was the short form of the health-related quality of life questionnaire (WHOQoL-BREF).…”
Section: Tablementioning
confidence: 99%