Cognitive Behavioral Therapy in Primary Care for Youth Declining Antidepressants: A Randomized Trial

Clarke, Gregory N.; DeBar, Lynn; Pearson, John; Dickerson, John F.; Lynch, Frances L.; Gullion, Christina M.; Leo, Michael C.

doi:10.1542/peds.2015-1851

Cited by 38 publications

(45 citation statements)

References 50 publications

(62 reference statements)

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“…These findings are consistent with studies, which also found 21 that TAU groups did not show significant improvement in depressive symptoms as compared to CBT groups (Clarke, et al, 2016;Hallgren, et al, 2015;Mukthar, et al, 2011;Shen et al, 2006). Based on author's observation and informal reports from patient in TAU group, few reasons were identified for the minimal improvement in this group.…”

Section: All the Measures Of Risk Factors Showed Medium (Dass-s Dasssupporting

confidence: 88%

Positive effects of Individual Cognitive Behavior Therapy for patients with unipolar mood disorders with suicidal ideation in Malaysia: A randomised controlled trial

Sinniah

Oei

Maniam

et al. 2017

Psychiatry Research

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The aim of this study was to investigate the effectiveness of Individual Cognitive Behavior Therapy (ICBT) in treating patients with mood disorders with suicidal ideation. A total of 69 patients (48 females, 21 males) with the diagnoses above were randomly allocated to either the group of Treatment As Usual (TAU) + ICBT (n=33) or the TAU group (n=36). All participants completed the Beck Depression Inventory (BDI), Beck Scale for Suicide Ideation (BSS), Positive and Negative Suicide Ideation Inventory (PANSI), Beck Hopelessness Scale (BHS), and Depression Anxiety Stress Scale-21 (DASS-21).These questionnaires were administered at pretreatment, midway through treatment (week 4), post-treatment (week 8), and at follow-ups after three months (week 20) and six months (week 32). Factorial ANOVA results showed that the TAU+ICBT patients improved significantly and at faster rate as compared to the TAU group, which showed improvement only from pre to mid treatment on DASS-D and BHS-T measures. The effect size (Cohen's d), for the TAU+ICBT group showed large effect (1.47) for depressive symptoms and suicidal ideation (1.00). These findings suggest that ICBT used in addition to the TAU, was effective in enhancing treatment outcome of patients with unipolar mood disorders as well as, reducing risk for suicide behavior.

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Section: All the Measures Of Risk Factors Showed Medium (Dass-s Dasssupporting

confidence: 88%

Positive effects of Individual Cognitive Behavior Therapy for patients with unipolar mood disorders with suicidal ideation in Malaysia: A randomised controlled trial

Sinniah

Oei

Maniam

et al. 2017

Psychiatry Research

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“…The preliminary findings outlined in this paper suggest that further development and testing of BA strategies could enhance the armamentarium of effective approaches in the field. BA expands upon the activation and pleasant events scheduling that is already included as an initial or elective component of most CBT approaches adapted for adolescents (Brent & Poling, 1997; Clarke, DeBar, Ludman, Asarnow, & Jaycox, 2002). Many of these programs also build in the option of using only the activation/pleasant events module in recognition that this may be sufficient to effect change for a subset of depressed youth (Clarke et al, 2002).…”

Section: Discussionmentioning

confidence: 99%

“…BA expands upon the activation and pleasant events scheduling that is already included as an initial or elective component of most CBT approaches adapted for adolescents (Brent & Poling, 1997; Clarke, DeBar, Ludman, Asarnow, & Jaycox, 2002). Many of these programs also build in the option of using only the activation/pleasant events module in recognition that this may be sufficient to effect change for a subset of depressed youth (Clarke et al, 2002). Moreover, BA employs functional analysis to address issues that get in the way of change, and focuses on overcoming avoidance, both of which are factors that may boost and maintain treatment response.…”

Section: Discussionmentioning

confidence: 99%

The Adolescent Behavioral Activation Program: Adapting Behavioral Activation as a Treatment for Depression in Adolescence

McCauley

Gudmundsen

Schloredt

et al. 2015

Journal of Clinical Child & Adolescent Psychology

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Objective This study aimed to examine implementation feasibility and initial treatment outcomes of a behavioral activation based treatment for adolescent depression, the Adolescent Behavioral Activation Program (A-BAP). Method A randomized, controlled trial was conducted with 60 clinically referred adolescents with a depressive disorder who were randomized to receive either 14 sessions of A-BAP or uncontrolled evidenced-based practice for depression (EBP-D). The urban sample was 64% female, predominantly Non-Hispanic White (67%) and had an average age of 14.9 years. Measures of depression, global functioning, activation and avoidance were obtained through clinical interviews and/or through parent and adolescent self-report at pre-intervention and end of intervention. Results Intent-to-treat linear mixed effects modeling and logistic regression analysis revealed that both conditions produced statistically significant improvement from pre- to end of treatment in depression, global functioning and activation and avoidance. There were no significant differences across treatment conditions. Conclusions These findings provide the first step in establishing the efficacy of BA as a treatment for adolescent depression and support the need for ongoing research on BA as a way to enhance the strategies available for treatment of depression in this population.

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“…A final possible explanation for differences between our cost-effectiveness findings and those in previous studies is the lack of a clear, clinical benefit of CBT in those studies. In the STAND (Study of Adolescents and Depression) study, 30 researchers found a clear, marked benefit of CBT compared with usual care in the primary outcomes and secondary depression-related outcome measures.…”

Section: Discussionmentioning

confidence: 99%

Cost-effectiveness of Cognitive Behavioral Therapy for Depressed Youth Declining Antidepressants

et al. 2018

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Cognitive Behavioral Therapy in Primary Care for Youth Declining Antidepressants: A Randomized Trial

Abstract: BACKGROUND AND OBJECTIVE: Health care providers have few alternatives for youth depression other than antidepressants. We examined whether brief cognitive behavioral therapy (CBT) is a viable alternative in primary care.

Cited by 38 publications

References 50 publications

Positive effects of Individual Cognitive Behavior Therapy for patients with unipolar mood disorders with suicidal ideation in Malaysia: A randomised controlled trial

Positive effects of Individual Cognitive Behavior Therapy for patients with unipolar mood disorders with suicidal ideation in Malaysia: A randomised controlled trial

The Adolescent Behavioral Activation Program: Adapting Behavioral Activation as a Treatment for Depression in Adolescence

Cost-effectiveness of Cognitive Behavioral Therapy for Depressed Youth Declining Antidepressants

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