“…Our findings are consistent with previous reports that children and adolescents diagnosed as having CD may have an increased vulnerability for developing anxiety (7,30); however, prevalence rates still need to be empirically established. Accordingly, these issues are particularly important for youth managing CD because gastrointestinal symptoms associated with psychological distress, or conditioned functional pain, may be misinterpreted as disease symptoms (9,16,(34)(35)(36). These data suggest that for some, anxiety is likely present even in the absence of disease activity.…”