Cognitive-Behaviour Therapy and Medication in the Treatment of Obsessive-Compulsive Disorder: A Controlled Study

O’Connor, Kieron; Todorov, Cristo; Robillard, Sophie; Borgeat, François; Brault, Mathilde

doi:10.1177/070674379904400108

Cited by 57 publications

(30 citation statements)

References 29 publications

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“…Patients who received ERP were less likely to take antidepressants at a 1-year follow-up. A small sample study comparing CBT and medication in the treatment of OCD provided evidence in favor of the combination (O'Connor et al 1999). A recent and important controlled trial by Foa et al (2005) tested the relative and combined efficacy of clomipramine and ERP in the treatment of OCD in adults.…”

Section: Psychotherapy and Pharmacotherapymentioning

confidence: 97%

Combining Pharmacotherapy with Cognitive‐Behavioral Interventions for Obsessive‐Compulsive Disorder

Cottraux¹,

Bouvard

Milliery³

2005

Cognitive Behaviour Therapy

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This paper reviews the evidence-based literature concerning the efficacy and effectiveness of cognitive behavior therapy (CBT), drug treatment and their combination for obsessive compulsive disorder (OCD). After a brief outline of the seminal studies, the state of the art is presented with reference to the consensual recommendations proposed in the last 10 years. Management of OCD rests on potent selective serotonin reuptake inhibitors and CBT, used separately, sequentially, or concurrently. A hierarchical model for clinical decision-making is reported. With greater severity of OCD, it is recommended to add medications. However, the response rate is still too low in many patients, and some patients remain refractory to any kind of treatment. This stresses the importance of joint efforts of psychological and biological teams to develop new treatments.

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Section: Psychotherapy and Pharmacotherapymentioning

confidence: 97%

Combining Pharmacotherapy with Cognitive‐Behavioral Interventions for Obsessive‐Compulsive Disorder

Cottraux¹,

Bouvard

Milliery³

2005

Cognitive Behaviour Therapy

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“…This enhances generalizability to ordinary clinical outpatient practice. However, it is possible that medication use facilitated some participants' abilities to engage in E/RP and/or cognitive therapy (O'Connor, Todorov, Robillard, Borgeat, & Brault, 1999).…”

Section: Limitations Of the Present Studymentioning

confidence: 99%

Compulsive behaviours and levels of belief in obsessive–compulsive disorder: a case-series analysis of their interrelationships

Storchheim

O’Mahony

2006

Clin. Psychol. Psychother.

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This study examined interrelationships of changes in compulsive behaviours and two levels of belief over treatment of obsessive-compulsive disorder (OCD). Levels were individual-specific obsessive beliefs (termed here manifest beliefs) and OCD-relevant general beliefs. If OCD-relevant general beliefs are functionally linked to manifest beliefs and compulsive behaviours, changes in compulsive behaviours and both belief types should occur mostly in tandem, even if only one or two of these three elements are explicitly targeted. Baselines consisting of time performing compulsive behaviours, strength of manifest belief and strength of OCD-relevant general beliefs were monitored daily by six participants over three phases in an A/B/B + C design. (A = no treatment, B = exposure/response prevention and C = cognitive therapy targeting only OCD-relevant general beliefs.) Changes in compulsive behaviours, manifest beliefs and OCD-relevant general beliefs moved primarily in tandem over treatment phases, suggesting functional links between these elements.

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“…In particular, Cottraux et al [41]showed that SSRI + BT compared to placebo + BT gives better results at 3 months on rituals and at 6 months on depression with equivalent results at 12 and 18 months. Moreover, a more recent but small sample study comparing CBT and medication in the treatment of OCD provided evidence in favor of the combination [42]. OCD patients received 1 of 4 treatments: medication and CBT simultaneously; CBT only; medication while on a waiting list for CBT, or no treatment while on a waiting list for CBT.…”

Section: Therapeutic Strategiesmentioning

confidence: 99%

Management of Obsessive Compulsive Disorder

Bouvard¹,

Milliery²,

Cottraux³

2004

Psychother Psychosom

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Cognitive-Behaviour Therapy and Medication in the Treatment of Obsessive-Compulsive Disorder: A Controlled Study

Abstract: Objective: To evaluate the effect ofcombining cognitive-behaviour therapy (CBT)

Cited by 57 publications

References 29 publications

Combining Pharmacotherapy with Cognitive‐Behavioral Interventions for Obsessive‐Compulsive Disorder

Combining Pharmacotherapy with Cognitive‐Behavioral Interventions for Obsessive‐Compulsive Disorder

Compulsive behaviours and levels of belief in obsessive–compulsive disorder: a case-series analysis of their interrelationships

Management of Obsessive Compulsive Disorder

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