Cognitive behavioral therapy (CBT) is an effectiveness-proven therapy method in the psychosocial treatment of childhood internalizing disorder. Considering the techniques included, even though anxiety and major depression are two different disorders, they are observed to occupy a quite common pool in terms of their similar nature, symptoms, etiologies, and high comorbidity rates. While these techniques are rationally similar to those in adult CBT, application ways, contents, session structures of the techniques, and styles of homework should be adapted to the developmental characteristics of children. In this book chapter, initially, several CBT programs for childhood internalizing disorders will be mentioned. After than, main points to take into consideration while adapting CBT, which was firstly designed for adults to children, will be emphasized. Lastly, information about main CBT techniques, whose effectiveness has been proven in the treatment of internalizing disorders, will be given.