Cognitive decline in Sprague–Dawley rats induced by neuroplasticity changes after occlusal support loss
Xiaoyu Wang,
Qian Pang,
Jiangqi Hu
et al.
Abstract:BackgroundTooth loss is closely related to cognitive impairment, especially affecting cognitive functions involving hippocampus. The most well‐known function of the hippocampus is learning and memory, and the mechanism behind is neuroplasticity, which strongly depends on the level of brain‐derived neurotrophic factor (BDNF). While research has delved into the possible mechanisms behind the loss of teeth leading to cognitive dysfunction, there are few studies on the plasticity of sensory neural pathway after to… Show more
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