Cognitive deficits of patients with chronic kidney disease and effect of hemodialysis

Egbi, Oghenekaro Godwin; Ogunrin, Olubunmi; Oviasu, Efosa

doi:10.15580/gjms.2015.1.012315013

Cited by 2 publications

(3 citation statements)

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“…This finding is compatible with previous reports. [ 10 16 ] Our observation suggests that ESRD patients may be at higher risk of memory impairment than the general population. Similarly, there was demonstrable reduced performance in attention, concentration, visual processing speed, motor activation and fluency and psychomotor performance in ESRD patients.…”

Section: Discussionmentioning

confidence: 79%

“…[ 22 23 ] However, relative reduction in attention and concentration seen in the current study is in contrast with the finding of Egbi et al . [ 10 ] This difference may not be unconnected with methodological differences. Cognitive symptoms appear to represent one of the core features of depressive disorders with an impact on many functional outcomes;[ 24 25 ] thus, deliberate effort was made in the present study to exclude depression and severe functional disability in the study patients.…”

Section: Discussionmentioning

confidence: 99%

“…[ 6 7 ] Earlier studies have demonstrated that renal transplantation is associated with improvements in both neuropsychological tests such as the mini-mental state examination (MMSE), and neurophysiological markers of cognitive function measured using evoked potential latencies and electroencephalographic rhythms. [ 8 9 10 ] This cognitive impairment does not only have implication for the patient's ability to participate in adequate care of the ESRD[ 3 ] but also have major implications for informed consent in relation to dialysis initiation or maintenance, and ultimately, renal transplantation. [ 11 12 ]…”

Section: Introductionmentioning

confidence: 99%

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Cognitive function assessment in patients with end- stage renal disease in Nigeria: A single center experience

et al. 2016

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Aim:The purpose of this comparative study was to evaluate cognitive function in end-stage renal disease (ESRD) patients in comparison with age, sex, and level of education-matched control.Materials and Methods:This is a cross-sectional study involving 80 ESRD patients receiving maintenance hemodialysis treatment and recruited conservatively at the nephrology unit of our hospital. Eighty apparently healthy control, that were matched with the patients for age, sex and education, were also recruited. Following exclusion of depression and severe functional disability, a computer-assisted neuropsychological test, the FePsy, was used to assess memory, psychomotor speed, concentration and attention using simple auditory and visual reaction time tasks, recognition memory tests (RMTs), finger tapping task, and binary choice task (BCT) for both the ESRD patients and controls.Results:ESRD patients performed worse on simple auditory and visual reaction time tasks (P < 0.05), RMTs (P < 0.05), finger tapping task (P < 0.05), BCT, and computerized visual search task (P < 0.05).Conclusion:Performance in memory, psychomotor tasks, concentration, and attention tasks were found to be reduced among patients with ESRD compared with age, sex and level of education-matched control.

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Section: Discussionmentioning

confidence: 79%