Cognitive Disorders in Patients with Multiple Sclerosis

Šehanović, Aida; Smajlović, Dževdet; Tupković, Emir; Ibrahimagić, Omer Ć.; Kunić, Suljo; Dostović, Zikrija; Zoletic, Emina; Pašić, Zejneba

doi:10.5455/msm.2020.32.191-195

Cited by 8 publications

(6 citation statements)

References 20 publications

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“…This phenomenon can be quantified by a decrease of tVSA and qVSA and an increase in FCR [14,19]. Such findings have been reported in a number of studies comparing acoustic formant-based parameters in patients affected by PD with matched healthy controls [20][21][22][23][24][25][26]. Acoustic analysis of voice and vowel metrics has been also applied to MS, detecting significant differences with healthy controls [27].…”

Section: Introductionmentioning

confidence: 90%

Models and Analysis of Vocal Emissions for Biomedical Applications

2023

Proceedings E Report

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The International Workshop on Models and Analysis of Vocal Emissions for Biomedical Applications (MAVEBA) came into being in 1999 from the particularly felt need of sharing know-how, objectives and results between areas that until then seemed quite distinct such as bioengineering, medicine and singing. MAVEBA deals with all aspects concerning the study of the human voice with applications ranging from the newborn to the adult and elderly. Over the years the initial issues have grown and spread also in other fields of research such as occupational voice disorders, neurology, rehabilitation, image and video analysis. MAVEBA takes place every two years in Firenze, Italy. This edition celebrates twenty-four years of uninterrupted and successful research in the field of voice analysis.

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Section: Introductionmentioning

confidence: 90%

Models and Analysis of Vocal Emissions for Biomedical Applications

2023

Proceedings E Report

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“…The studies conducted on EF in pMS are not easily comparable due to the high conceptual and methodological variability; in general, it is established that, in pMS, EF are altered with different degrees and frequency (20 to 80%). 35 While some authors believe that, in MS, EF deficits have a lower prevalence than memory deficits, 7 36 others declare a higher prevalence of the former. 37…”

Section: Cognitive Impairment In Msmentioning

confidence: 99%

Cognitive impairment in multiple sclerosis: “classic” knowledge and recent acquisitions

2023

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Multiple sclerosis (MS) is a central nervous system (CNS) disease characterized by inflammation, axonal demyelination, and neurodegeneration, which can have a strong impact on all aspects of the life of the patient. Multiple sclerosis causes motor, sensory, cerebellar, and autonomic dysfunctions, as well as cognitive and psychoemotional impairment. The most frequently compromised cognitive domains are complex attention/information processing, memory, executive and visuospatial functions. Recently, alterations have also been evidenced in complex cognitive functions, such as social cognition, moral judgment, and decision-making. Cognitive impairment is characterized by high variability and can affect work skills, social interactions, coping strategies and more generally the quality of life of patients and their families. With the use of sensitive and easy-to-administer test batteries, an increasingly accurate and early diagnosis is feasible: this allows to determine the effectiveness of possible preventive measures, to predict the future progression of the disease and to improve the quality of life of patients. There is currently limited evidence regarding the efficacy, on cognitive impairment, of disease-modifying therapies. The most promising approach, which has received strong empirical support, is cognitive rehabilitation.

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“…The cognitive domains recognized as mainly impaired in MS are memory, in its different dimensions [ 11 ], attention [ 12 ], and executive functions [ 13 ], allowing us to identify different phenotypes of cognitive impairments that represent a more meaningful concept of the cognitive status of people with MS [ 14 ]. Therefore, the performance of various daily activities is commonly compromised by cognitive deficits [ 15 ].…”

Section: Introductionmentioning

confidence: 99%

Integrated Cognitive Rehabilitation Home-Based Protocol to Improve Cognitive Functions in Multiple Sclerosis Patients: A Randomized Controlled Study

Sharbafshaaer

Trojsi

Bonavita

et al. 2022

JCM

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Cognitive impairment (CI) occurs in about 40–65% of people with multiple sclerosis (MS) during the disease course. Cognitive rehabilitation has produced non-univocal results in MS patients. Objective: The present study aimed to evaluate whether an Integrated Cognitive Rehabilitation Program (ICRP) in MS patients might significantly improve CI. Methods: Forty patients with three phenotypes of MS were randomly assigned into two groups: the experimental group (EG, n = 20), which participated in the ICRP for 10 weeks of training; and the control group (CG, n = 20). All participants’ cognitive functions were assessed at three timepoints (baseline, post-treatment, and 3-month follow-up) with the California Verbal Learning (CVLT), Brief Visuospatial Memory (BVMTR), Numerical Stroop, and Wisconsin tests. Results: When compared to CG patients, EG patients showed significant improvements in several measures of cognitive performance after ICRP, including verbal learning, visuospatial memory, attention, and executive functions. Conclusions: Home-based ICRP can improve cognitive functions and prevent the deterioration of patients’ cognitive deficits. As an integrated cognitive rehabilitation program aimed at potentiation of restorative and compensatory mechanisms, this approach might suggest an effective role in preserving neuronal flexibility as well as limiting the progression of cognitive dysfunction in MS.

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Cognitive Disorders in Patients with Multiple Sclerosis

Cited by 8 publications

References 20 publications

Models and Analysis of Vocal Emissions for Biomedical Applications

Models and Analysis of Vocal Emissions for Biomedical Applications

Cognitive impairment in multiple sclerosis: “classic” knowledge and recent acquisitions

Integrated Cognitive Rehabilitation Home-Based Protocol to Improve Cognitive Functions in Multiple Sclerosis Patients: A Randomized Controlled Study

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