Cognitive Disturbances and Regional Cerebral Blood Flow Abnormalities in Migraine Patients: Their Relationship with the Clinical Manifestations of the Illness

Calandre, Elena P.; Bembibre, Judit; Arnedo, ML; Becerra, Diana

doi:10.1046/j.1468-2982.2002.00370.x

Cited by 165 publications

(206 citation statements)

References 28 publications

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“…One study assessed verbal memory and EF in active episodic CH (ECH) and reported only decreased auditory verbal memory as compared with tension headache patients (16), an impairment that could also be shown in migraine patients (17). As pain may interfere with cognitive performance (18), it is unclear whether pain itself (15) or the underlying headache pathology results in decreased test scores.…”

Section: Introductionmentioning

confidence: 99%

Cluster headache and neuropsychological functioning

et al. 2012

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Background: Despite significant advances in unravelling the pathophysiology of cluster headache (CH), little is known about neuropsychological functioning. Apart from neuroimaging studies indicating involvement of posterior hypothalamic and other areas frequently involved in nociception, some studies suggest involvement of prefrontal areas. Among others, these mediate executive functioning (EF). Methods: Therefore, three neuropsychological tests (Trail Making Test (TMT), Go/Nogo Task and Stroop Task) were completed by four headache patient samples (chronic CH, episodic CH in the active or inactive period, and migraine patients) and compared to healthy controls. Results: Analyses revealed that patients especially with chronic and active episodic CH were particularly impaired in tests relying more on intact EF (i.e. TMT-B, Stroop interference) than on basal cognitive processes (i.e. TMT-A, Stroop naming). Within the CH groups performance decreased linearly with increasing severity. Discussion: These findings are in line with a recently proposed involvement of prefrontal structures in CH pathophysiology as patients performed worse on neuropsychological tasks relying on these structures. Impaired EF could also result from medication and sleep disturbances due to active CH. Because the decreased performance was also present outside the attacks it may hint at generally altered brain functions, but do not necessarily reflect clinically relevant behaviour.

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Section: Introductionmentioning

confidence: 99%

Cluster headache and neuropsychological functioning

et al. 2012

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“…In the adult population studies, Calandre et al 9 reported deficits of attention, memory, and information speed in migraineurs when compared to a control group. Le Pira et al 10 compared 30 individuals with migraine to a control group and showed that immediate and delayed memory were impaired in the migraine group.…”

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confidence: 99%

Migraine and cognition in children: a controlled study

Moutran

Villa

Diaz

et al. 2011

Arq. Neuro-Psiquiatr.

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Objective: Evaluate the cognitive functions of children with migraine and compare them to A control group. Method: 30 migraineur children and 30 control group children without migraine, age ranging from 8 to 12 years old, were subjected to a cognitive functions assessment with Wechsler Intelligence Scale for Children (WISCIII). Results: Although both groups had a normal cognitive performance, children with migraine had significantly worse scores compared to the control group in the subtests of Information, Arithmetic, Vocabulary, Object Assembly and in the Indexes of Perceptual Organization, Resistance to Distraction and Processing Speed. Conclusion: Children with migraine had impairment in some cognitive functions such as attention, memory, information speed, and perceptual organization compared to the control group.

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“…It was hypothesized that persistent abnormalities in cerebral blood flow causing neuronal disturbances and a complex neurotransmitter disorder may account for reduced short-and long-term memories in migraine patients [22,33]. However, other studies found neither detrimental cognitive effects in migraine patients nor differences between migraineurs with and without aura, when they were assessed interictally [34][35][36].…”

Section: Discussionmentioning

confidence: 99%

Neuropsychologic phenotypes in familial hemiplegic migraine

Roccella

2003

J Headache Pain

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The 3 adolescents studied are from a large family in which the mother and 6 of 8 children are affected by FHM. The affected children are 4 males aged 33, 30, 15 and 13 years, and 2 females aged 30 and 10 years. Convulsions with fever were reported by the Michele RoccellaAbstract Familial hemiplegic migraine (FHM) is a rare autosomal dominant-type migraine with aura. Attacks are characterised by hemiparesis in addition to other aura and migraine symptoms. Few studies have examined the influence of FHM on cognitive functions. This study was aimed to investigate neuropsychological functions in 3 adolescent siblings suffering from FHM assessed six months after the last attack. No relevant deficits were found on a battery of multisectorial tests exploring cognitive functions. Sporadic FHM attack therefore seems not to affect cognition in these patients, at least far from the crises.

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Cognitive Disturbances and Regional Cerebral Blood Flow Abnormalities in Migraine Patients: Their Relationship with the Clinical Manifestations of the Illness

Cited by 165 publications

References 28 publications

Cluster headache and neuropsychological functioning

Cluster headache and neuropsychological functioning

Migraine and cognition in children: a controlled study

Neuropsychologic phenotypes in familial hemiplegic migraine

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