2020
DOI: 10.1177/1526924820958144
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Cognitive Function in Liver Transplant Recipients Who Survived More Than 6 Months

Abstract: Introduction: Current research in the areas of liver transplant and cognitive function has primarily examined cognitive changes from pre- to 1-year posttransplant, resulting in an insufficient understanding of cognitive trajectory beyond early periods of transplant and its impact on self-management. This study aimed (1) to describe global and domain-specific cognitive function in liver transplant recipients who survived more than 6 months after transplant and (2) to describe patient and clinical characteristic… Show more

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Cited by 6 publications
(22 citation statements)
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“…Our study extends this previous literature by using a psychometrically sound measure to assess subjective cognition reported by LT recipients and their caregivers. This study also purposely assessed the domains of visuospatial abilities, executive function, and attention, as these domains are most commonly affected following LT. (19,20) In line with the previous findings, our results suggest that subjective LT recipient ratings correlated with visuospatial abilities. However, subjective caregiver ratings appeared to correlate with objective cognition more broadly including global cognition, visuospatial abilities, organization, and attention.…”
Section: Discussionsupporting
confidence: 92%
See 1 more Smart Citation
“…Our study extends this previous literature by using a psychometrically sound measure to assess subjective cognition reported by LT recipients and their caregivers. This study also purposely assessed the domains of visuospatial abilities, executive function, and attention, as these domains are most commonly affected following LT. (19,20) In line with the previous findings, our results suggest that subjective LT recipient ratings correlated with visuospatial abilities. However, subjective caregiver ratings appeared to correlate with objective cognition more broadly including global cognition, visuospatial abilities, organization, and attention.…”
Section: Discussionsupporting
confidence: 92%
“…After completing the ECog online, LT recipients completed in-person, paper-and-pencil objective cognitive tests. Global cognition and 3 domains of cognition (visuospatial abilities, executive function, and attention), the most commonly impaired domains among LT recipients, (19,20) were assessed. The Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) was used to assess global cognition.…”
Section: Objective Cognitionmentioning
confidence: 99%
“…Median (Q1-Q3) time between pre-LT MoCA and LT was 7 (3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13) months and between LT and post-LT MoCA was 7 (5)(6)(7)(8)(9)(10)(11)…”
Section: Resultsmentioning
confidence: 99%
“…Cognition in three domains most commonly found to be impaired in the LT population (visuospatial abilities, executive function, and attention) ( 7 , 23 ) were additionally assessed using reliable and valid cognitive tests. The Trail Making Test Parts A and B assess attention and executive function, respectively, and longer total time to complete the test indicates worse cognition ( 24 ).…”
Section: Methodsmentioning
confidence: 99%
“…Cognitive decline could be one of the potential factors that prevent successful performance of such activities. In fact, 9%–56% of LT recipients have objective impairment on formal cognitive testing ( 7 9 ).…”
Section: Introductionmentioning
confidence: 99%