Cognitive Function is a Predictor of Home Discharge in Subacute Stroke Patients: A Retrospective Cohort Study

Abstract

Background: To investigate the cognitive function and its relation to home discharge of patients following subacute stroke.Methods: This retrospective cohort study included 1,229 convalescent patients experiencing first subacute stroke. We determined discharge destination and demographic and clinical information. We recorded the following measurement scores: Mini-Mental State Examination (MMSE) score, Stroke Impairment Assessment Set score, grip strength, and Functional Independence Measure (FIM). We performed a multivariate logistic regression analysis to identify factors related to home discharge. Results: Of the 1,229 participants (mean age: 68.7±13.5 years), 501 (40.8%), 735 (59.8%), and 1,011 (82.3%) were female, had cerebral infarction, and were home discharged, respectively. Multivariate logistic regression analysis revealed that age (odds ratio [OR], 0.93; 95% confidence interval [CI], 0.91–0.96; P<0.001), duration from stroke onset to admission (OR, 0.98; 95% CI, 0.96–0.99; P=0.003), living situation (OR, 4.40; 95% CI, 2.69–7.20; P<0.001), MMSE score at admission (OR, 1.05; 95% CI, 1.00–1.09; P=0.035), FIM motor score at admission (OR, 1.04; 95% CI, 1.01–1.06; P=0.001), and FIM cognitive score at admission (OR, 1.08; 95% CI, 1.04–1.13; P<0.001) were significantly associated with home discharge. Conclusions: MMSE at admission may be a useful indicator for predicting home discharge.