2012
DOI: 10.1016/j.ophtha.2012.04.026
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Cognitive Impairment in Age-related Macular Degeneration and Geographic Atrophy

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Cited by 88 publications
(83 citation statements)
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References 22 publications
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“…[5][6][7][8][9] After multivariate adjustment, they found no association between dementia (OR, 1.0; 95% CI, 0.6-1.7), AD (1.1; 0.6-2.1), or low modified MMSE (1.2; 0.8-1.9) and early AMD. By contrast, they did report a positive association between cognitive impairment based on digit symbol substitution test and early AMD (OR, 2.0; 95% CI, 1.3-3.1).…”
Section: Discussionmentioning
confidence: 99%
“…[5][6][7][8][9] After multivariate adjustment, they found no association between dementia (OR, 1.0; 95% CI, 0.6-1.7), AD (1.1; 0.6-2.1), or low modified MMSE (1.2; 0.8-1.9) and early AMD. By contrast, they did report a positive association between cognitive impairment based on digit symbol substitution test and early AMD (OR, 2.0; 95% CI, 1.3-3.1).…”
Section: Discussionmentioning
confidence: 99%
“…Based on the epidemiological studies again, we do not have a clear answer as to whether incidence of cognitive impairment or AD is more common in AMD or glaucoma subjects or otherwise if the reverse of this true. While some studies found an association between either glaucoma or AMD and cognitive impairment [14,15]; others showed no significant association [16,17].…”
Section: Introductionmentioning
confidence: 99%
“…A South Korean study of 170 AMD patients and 190 non-AMD community-based controls showed that visuospatial function, verbal memory, visual memory, and frontal function were impaired in AMD patients vs. controls. Mild cognitive impairment was also higher in AMD patients than in controls (52.4% vs. 26.8%; P<0.001), with the greatest cognitive impairment in those patients with poor visual acuity (≤ 20/100) [40].…”
Section: Depressionmentioning
confidence: 88%
“…In elderly patients, visual impairment is associated with increased cognitive decline [40,41]. A South Korean study of 170 AMD patients and 190 non-AMD community-based controls showed that visuospatial function, verbal memory, visual memory, and frontal function were impaired in AMD patients vs. controls.…”
Section: Depressionmentioning
confidence: 99%