Cognitive Potentials

Mickleborough, Marla; Sun, Guangming; Moss, Daneil; Kriegler, Conley

doi:10.1007/978-3-030-56538-1_4

Cited by 1 publication

(4 citation statements)

References 42 publications

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Section: Discussionmentioning

confidence: 99%

“…Migraine has been associated with attentional abnormalities through subjective reports [15,52,78], neuropsychological tests [89,92], or EEG and event-related potentials (ERPs) studies [65]. However, little is known on the functional role of brain oscillations in the disruption of attention in migraine.…”

Section: Discussionmentioning

confidence: 99%

“…The apparent inability of migraineurs to suppress irrelevant information may be part of the neurophysiological underpinning of their complaints of attention difficulties and increased distractibility in their daily life [15,52,65,78]. The characterization of attentional alterations associated with migraine might inform therapeutical strategies to improve their daily life and possibly reducing the attack frequency.…”

Section: Discussionmentioning

confidence: 99%

“…We measure alpha and gamma power as markers of top-down and bottom-up attentional processes, respectively. Based on previous work with other brain signals [61,65], we expected alterations for both top-down and bottom-up mechanisms.…”

Section: Introductionmentioning

confidence: 99%

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Top-down inhibition of irrelevant information indexed by alpha rhythms is disrupted in migraine

Masson

ElShafei

Demarquay

et al. 2021

Preprint

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There is growing evidence that migraine is associated with attentional abnormalities, both during and outside migraine attacks, which would impact the cognitive processing of sensory stimulation. However, these attention alterations are poorly characterized and their neurophysiological basis is still unclear. Nineteen migraineurs without aura and nineteen healthy participants were recruited to perform a task which used visually-cued auditory targets and distracting sounds to evaluate conjointly top-down and bottom-up attention mechanisms. Magnetoencephalography (MEG) signals were recorded. We investigated anticipatory alpha activity (power increase and decrease) and distractor-induced gamma activity as markers for top-down (inhibition and facilitation) and bottom-up attention, respectively. Compared to healthy participants, migraineurs presented a significantly less prominent alpha power increase in visual areas in anticipation of the auditory target, indexing a reduced inhibition of task-irrelevant visual areas. However, there was no significant group difference regarding the alpha power decrease in the relevant auditory cortices in anticipation of the target, nor regarding the distractor-induced gamma power increase in the ventral attention network. These results in the alpha band suggest that top-down inhibitory processes in the visual cortices are deficient in migraine but there is no clear evidence supporting a disruption of top-down facilitatory attentional processes. This relative inability to suppress irrelevant sensory information may be underlying the self-reported increased distractibility and contribute to sensory disturbances in migraine.

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