5G communication system is rapidly taking shape and for many organizations, including administrations, it is important to be aware of developments in this regard. At this stage, it is essential to know about 5G use cases and possible key technologies. This paper describes several anticipated 5G use cases across a handful of different sectors. It is important to remember that these comprise only a subset of possible use cases and these are all still new. As-yet more new use cases are expected to emerge and the need to prepare their adaption in 5G and beyond. From wireless transmission, wireless access and network perspectives, the possible key technologies of 5G, including Massive Multiple Input Multiple Output (MIMO), Beam-forming, Device-to-Device communication system (D2D), non-orthogonal multiple access (NOMA), Full duplex, Small cells, cognitive radio(CR), etc. and their latest progress are presented comprehensively and thoroughly. Each has enormous advantages but also limitations. The Full duplex which will help to double the capacity of the channel compared to the Half-duplex technology of 4G and Small cells combined with millimeter waves to have a wide bandwidth. These Small-Cells are essential for energy reduction and also for improving latency. But these Small-Cells require the use of intelligent antennas, that is to say, the diagrams of which are directive and reconfigurable at the request of the user Future research challenges regarding 5G and beyond wireless communication are also discussed.