Cognitive recovery after ambulatory anaesthesia based on desflurane or propofol: a prospective randomised study

Abstract

Cognitive recovery was not complete 1 week after surgery in any of the groups. There was no difference in the rate of cognitive recovery in middle-aged patients receiving desflurane or propofol anaesthesia during ambulatory breast surgery.

Validation of the cognitive recovery assessments with the Postoperative Quality of Recovery Scale in patients with low‐baseline cognition

“…Recovery improved over time in both normal and low‐baseline groups in a manner that is consistent with previous data , indicating that the new scoring system produces similar results in low‐baseline participants to the normal baseline participants. This similarity of cognitive recovery between groups that have normal vs. low‐baseline cognition has potentially important clinical implications given the current debate regarding the relationship between pre‐existing cognitive impairment and poor postoperative cognitive function , and emphasises the need to validate a scoring system with which to measure cognitive recovery in those patients with a low pre‐operative baseline.…”

Cognitive testing with the Post‐Operative Quality of Recovery Scale in pre‐surgery cancer patients – a controlled study

“…However, we applied relatively long time periods between test rounds to minimise the learning effect, and time intervals as short as 30 min have been suggested to be a sufficient duration for patients to be unlikely to recall their previous answers . The time points for the re‐tests in the present study were similar to the ones in the original PQRS study as well as in our previous patient study . Royse et al.…”

“…We found in a recent study assessing cognitive recovery according to the PQRS in females after breast cancer surgery that some patients with a low baseline score improved their results considerably during the post‐operative period. We speculated that this improvement was an effect of a poor baseline performance due to stress and anxiety while waiting for cancer surgery and that this strain was partly relieved post‐operatively resulting in an improved cognitive performance . It is well known that malignant disease can affect cognitive performance …”

Ambulatory anaesthesia and cognitive dysfunction

“…In breast surgery patients there was also no difference in cognitive recovery using the PQRS, whether propofol or desflurane was used [18] when patients were assessed at 2, 20, and 48 h. Interestingly, only around 50% had fully recovered at 2 h. A study has also been done in children undergoing day-case dental surgery randomized to either propofol or isoflurane. Several cognitive tests were administered to assess recovery at a minimum of 60 min and again 24 h after the procedure.…”