Cognitive, Sensory and Motor Adjustment to Hemispherectomy

Bayard, Sophie; Lassonde, Maryse

doi:10.1007/0-306-47612-6_25

Cited by 8 publications

(7 citation statements)

References 37 publications

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“…69,71 There are numerous studies in which authors have assessed the cognitive abilities of patients after hemispheric surgery. While some show no change, 4,45 others show improvement in scores after hemispherectomy. 5,38,39,58 The presurgical developmental level seems to be important not only for the capacity of the brain to improve, 2 but also for seizure outcome.…”

Section: Neurosurg Focus / Volume 25 / September 2008mentioning

confidence: 97%

Hemispherotomy and other disconnective techniques

Ribaupierre

Delalande

2008

FOC

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The surgical treatment of intractable epilepsy has evolved as new technical innovations have been made. Hemispherotomy techniques have been developed to replace hemispherectomy in order to reduce the complication rates while maintaining good seizure control. Disconnective procedures are based on the interruption of the epileptic network rather than the removal of the epileptogenic zone. They can be applied to hemispheric pathologies, leading to hemispherotomy, but they can also be applied to posterior quadrant epilepsies, or hypothalamic hamartomas. In this paper, the authors review the literature, present an overview of the historical background, and discuss the different techniques along with their outcomes and complications.

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Section: Neurosurg Focus / Volume 25 / September 2008mentioning

confidence: 97%

Hemispherotomy and other disconnective techniques

Ribaupierre

Delalande

2008

FOC

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“…The epileptic lesion may also represent a more widespread pathology of cerebral organization that may limit cognitive potential (6)(7)(8)(9)(10). Some studies have reported that surgical treatment is able to improve cognition in children with epilepsy (19,20). As the developing brain possesses considerable functioning plasticity, long-term studies are needed.…”

Section: Introductionmentioning

confidence: 99%

Epilepsy surgery in children with drug-resistant epilepsy, a long-term follow-up

et al. 2013

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Epilepsy surgery in children offers suitable candidates a good chance of significantly improved outcome and low rates of complications. Several children, however, required a reoperation to achieve satisfactory seizure outcomes. Cognitive level was preserved, and the majority of patients followed their expected cognitive trajectory. Cognitive improvements in processing speed appear to occur in parallel with seizure control and were even more pronounced in subjects with no anti-epilepsy drugs. These improvements persisted even after long-term follow-up.

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“…Nevertheless, no study has yet described such an exceptional verbal postoperative outcome in a child with a single hemisphere (Bayard & Lassonde, 2001). Preoperatively, short-term memory weakness may be attributed to the cognitive slowdown commonly observed in RE, and it is tempting to speculate that our patient may regain a level that was most likely present prior to the onset of disease.…”

Section: Discussionmentioning

confidence: 76%

“…Hemispherotomy (H) is then recommended since around 60-90% of patients are subsequently seizure-free (Cross et al, 2006;Delalande et al, 2007). Cognitive functions seem to be globally stable after H (Bayard & Lassonde, 2001;Pulsifer et al, 2004), and etiologies do not have any effect on seizure outcome (Jonas et al, 2004). Delalande et al (2007) found, however, a correlation between preoperative delay and the Vineland Adaptive Behavior score in a large series with various etiologies (developmental, acquired, or progressive).…”

mentioning

confidence: 96%

Exceptional verbal intelligence after hemispherotomy in a child with Rasmussen encephalitis

et al. 2014

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We report a longitudinal case study of a left-handed girl who underwent left hemispherotomy at 7 years for Rasmussen encephalitis (RE). Presurgical evaluation showed mild hemiparesis, no visual defect, and light neuropsychological impairment with short-term memory weakness. Language fMRI showed a right hemispheric dominance. Postoperatively, the patient exhibited right hemiplegia and hemianopsia but preserved intellectual capacities. She became seizure-free, and antiepileptic medication was discontinued. Long-term follow-up showed very high verbal intelligence at 11 years of age (VCI of 155) and improvement in working memory as well as language and reading abilities. Furthermore, a significant visuoverbal discrepancy became increasingly pronounced. Thus, early surgical treatment of epilepsy avoided the global cognitive deterioration usually associated with RE. Finally, such a high level of verbal functioning combined with low spatial reasoning with a single hemisphere provides additional information on the neurocognitive profile of children with RE after hemispherotomy.

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Cognitive, Sensory and Motor Adjustment to Hemispherectomy

Cited by 8 publications

References 37 publications

Hemispherotomy and other disconnective techniques

Hemispherotomy and other disconnective techniques

Epilepsy surgery in children with drug-resistant epilepsy, a long-term follow-up

Exceptional verbal intelligence after hemispherotomy in a child with Rasmussen encephalitis

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