Coherent anti-Stokes Raman scattering microscopy with a photonic crystal fiber based light source

Abstract

A coherent anti-Stokes Raman scattering microscope based on a Ti:sapphire femtosecond oscillator and a photonic crystal fiber is demonstrated. The nonlinear response of the fiber is used to generate the additional wavelength needed in the Raman process. The applicability of the setup is demonstrated by imaging of micrometer-sized polystyrene beads.

Heterodyne detected nonlinear optical imaging in a lock‐in free manner

“…At the LO power below 1 mW, the TAMP improved the SNR by up to 10 times compared to LIA based detection. Such improvement opens the opportunity for high-speed, high-quality SRS imaging with low power sources such as Er: fiber lasers [20], photonic crystal fiber [21,22] or fiber optical parametric oscillator [23] recently developed as compact and cost-effective alternatives to solid state lasers.…”

Nonlinear optical microscopy in decoding arterial diseases

“…Stokes) involves the use of the output with only a single oscillator. There are various strategies for this approach: (1) using an optical parametric oscillator (OPO) (Ganikhanov et al 2006); (2) mixing the frequencies from a single high bandwidth pulse (Dudovich et al 2002); (3) generating new spectral components using a photonic crystal fiber (PCF) (Paulsen et al 2003). Figure 3 illustrates simplified configurations of OPO-and PCF-based multimodal CARS systems.…”

IR microscopy utilizing intense supercontinuum light source

“…Supercontinuum (SC) [5] generation in the visible spectral range has led to several breakthroughs in spectroscopy and imaging, most notably the development of the ultra-precise frequency comb used in optical metrology [6,7], but the broad spectrum has also been utilized in microscopy [8,9]. Recently, the supercontinuum technique was extended to the infrared spectral range beyond 2.6 μm by applying soft glass fibers such af ZBLAN [10,11].…”