Coherent Relations in EEGs of Adolescents with Partial Hearing Loss under Conditions of an Orthostatic Test

Шкуропат, А. В.

doi:10.1007/s11062-019-09763-2

Cited by 2 publications

(4 citation statements)

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“…Взаємовідносини таких ефектів носять динамічний характер та суттєво залежать від внутрішньої та зовнішньої аферентації у кожний момент. Зниження сенсорного притоку або його спотворення буде змінювати функціональний стан головного мозку [3][4][5].…”

Section: вступunclassified

“…Для формування адекватного функціонального стану мозку необхідний відпо відний притік від сенсорних систем. Раніше нами було показано, що ЕЕГ дітей із сенсоневральною приглухуватістю мала оз на ки недостатності активуючих впливів ре тикулярної формації середнього мозку та та ламокортикальних структур, активації синх ро нізуючих механізмів внаслідок зни ження тонусу ней ронів кори головного моз ку [5].…”

Section: вступunclassified

“…Роль α-ритму полягає у зв'язуванні всіх ділянок головного мозку та підготовці до здійснення майбутньої діяльності. Він генерується ядрами таламуса та по таламокортикальним зв'язкам розповсюджується по всьому скальпу [5,13]. Таламус є структурою головного мозку, яка бере участь у плануванні та задумі руху, оцінці його виконання та можливості корекції.…”

Section: результати та їх обговоренняunclassified

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Study of the Electroencephalogram of Children With Sensor and Motor Deprivation

Shkuropat,

Golovchenko,

Tarasova

et al. 2023

Fiziol Zh

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Sensorineural hearing loss and cerebral palsy (CP) are natural models of deprivation. In individuals with these pathologies, the rhythmic components of the electroencephalogram (EEG) of individual zones provide an opportunity to identify the central mechanisms of adaptive changes that develop at the system level. The normalized spectral power of EEG derivation was used in our study to assess the effect of auditory and motor deprivation on the functional state of the brain. The study involved 240 children aged 8 to 15 years who were divided into four groups: group I included 40 muffled boys and 42 girls; to II - 40 guys and 40 girls who heard; to III - 40 boys and 38 girls with impaired motor activity; to IV - 50 guys and 50 girls with normal physical activity. We found that children with limited motor activity had a lower normalized spectral power of the δ-rhythm in the posterior leads on the right side (respectively, girls - 27.23 ± 0.84 and 33.99 ± 1.94; boys - 27.80 ± 1.78 and 36.82 ± 2.04) and temporal from the left (respectively, girls - 27.40 ± 0.98 and 37.82 ± 1.66; boys - 39.88 ± 1.63 and 42.17 ± 2.04). An increase in the normalized spectral power of the θ-rhythm in the temporo-parietal-occipital region of the brain (respectively, girls – 25.73 ± 1.18 and 13.64 ± 0.47; boys – 19.86 ± 0.95 and 12.74 ± 0.78,), a lower normalized spectral power of the α-rhythm and a greater normalized spectral power of the β-rhythm (α-rhythm: respectively, girls – 24.34 ± 1.54 and 41.71 ± 2.54; boys – 27.84 ± 1.48 and 45.01 ± 2.41; β-rhythm: girls – 25.00 ± 1.14 and 9.95 ± 0.48; boys – 19.94 ± 0.86 and 9.20 ± 0.66) over almost the entire scalp compared to children with sensorineural hearing loss.

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Section: вступunclassified

Section: результати та їх обговоренняunclassified

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Study of the Electroencephalogram of Children With Sensor and Motor Deprivation

Shkuropat,

Golovchenko,

Tarasova

et al. 2023

Fiziol Zh

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“…The problem of any direction of cellular therapy of liver diseases will be the creation of an appropriate microenvironment of hepatocytes in vitro and the stimulation of the processes of proliferation, differentiation or individual functions of liver cells. The creation of a microenvironment of liver cells to prevent the loss of their characteristic phenotype is an equally important issue [6][7][8][9].…”

Section: Introductionmentioning

confidence: 99%

Influence of biologically active substances on synthesis function and cellular destruction of hepatocytes in vitro

Shkuropat¹,

Shvets²,

Golovchenko³

et al. 2022

Fiziol Zh

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The aim of the study was to reveal the effect of biologically active substances on the synthesis activity and cellular destruction of hepatocytes in vitro. Liver sections were prepared for investigation and placed in culture vials with DMEM nutrient medium with 15% calf serum, glucose, and antibiotics (streptomycin and penicillin). Liver sections were incubated for 14 days with interleukin-2 (roncoleukin) at a concentration of 5000 IU/ml and 7500 IU/ml, and erythropoietin (epobiocrine, “Biopharma”, USA) at a concentration of 13 IU/ml (high concentration), 6.5 IU/ml (medium concentration) and 1.3 IU/ml (low concentration) and without stimulation (control cultures). Synthesis activity and cellular destruction of hepatocytes were studied by determining the protein content, alanine aminotransferase and aspartate aminotransferase activity in the supernatant of liver organ cultures on the 7th and 14th days of incubation. It was found that culturing organotypic cultures with IL-2 did not affect the synthesis function of hepatocytes, but reduced aspartate aminotransferase activity throughout the culture period. At a concentration of 7500 IU/ml IL-2 showed a weak hepatotoxic effect. It was found that erythropoietin at a medium concentration had a hepatoprotective effect, at a high concentration it suppressed the synthesis activity of hepatocytes and contributed to the destruction of the cytoplasmic membrane of cells. At low concentrations, erythropoietin increased the synthesis activity of liver cells but caused an increase in the activity of aminotransferases, this may indicate both mass cell death and intensification of amino acid transamination processes. It was established that interleukin and its inhibitor cause biological effects when incubated with organotypic cultures.

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Coherent Relations in EEGs of Adolescents with Partial Hearing Loss under Conditions of an Orthostatic Test

Cited by 2 publications

References 4 publications

Study of the Electroencephalogram of Children With Sensor and Motor Deprivation

Study of the Electroencephalogram of Children With Sensor and Motor Deprivation

Influence of biologically active substances on synthesis function and cellular destruction of hepatocytes in vitro

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