The object of the present paper is to study the notion of quasi-bi-slant submanifolds of almost contact metric manifolds as a generalization of slant, semi-slant, hemi-slant, bi-slant, and quasi-hemi-slant submanifolds. We study and characterize quasi-bi-slant submanifolds of Sasakian manifolds and provide non-trivial examples to signify that the structure presented in this paper is valid. Furthermore, the integrability of distributions and geometry of foliations are researched. Moreover, we characterize quasi-bi-slant submanifolds with parallel canonical structures.