Cohort profile: maternal lifestyle and diet in relation to pregnancy, postpartum and infant health outcomes in Vietnam: A multicentre prospective cohort study

Abstract

PurposeTo determine modifiable maternal risk factors for adverse pregnancy, postpartum maternal and child health outcomes in Vietnam.ParticipantsThis prospective cohort study included pregnant women seeking prenatal care at six hospitals in three large cities in Vietnam. After enrolment, eligible participants who gave their consent to participate in the study were interviewed at 24–28 weeks' gestation. Glucose testing was conducted and blood pressure was measured during this period. Each participant will be assessed prospectively during their postnatal visits at delivery, 1, 3, 6, 12, 18 and 24 months, and will be followed up for 5 years.Findings to dateOf 2248 eligible pregnant women, 2030 were recruited (participation rate 90.3%) between August 2015 and July 2016. All participants completed the baseline assessment. Their mean (SD) age was 27.6 (5.3) years. The mean pre-pregnancy body mass index (BMI) was 20.2 (SD 2.6) kg/m2, with nearly two-thirds of participants having a normal pre-pregnancy BMI (18.5 to <23.0 kg/m2) and one-quarter being underweight (pre-pregnancy BMI <18.5 kg/m2). Overweight or obese mothers (pre-pregnancy BMI ≥23.0 kg/m2) accounted for 12.8%. No pregnant women reported smoking during their pregnancy while 13.4% of them had continued drinking. 22.8% of participants had hyperglycaemia. Their mean systolic blood pressure was 105.6 (SD 8.2) mm Hg, and diastolic blood pressure was 67.4 (SD 7.5) mm Hg.Future plansThe relationships of maternal lifestyle and nutritional status with the health outcomes of pregnancy, postpartum maternity and infants will be analysed. Meanwhile, participants will be closely tracked to minimise loss to follow-up.

Postpartum Physical Activity and Weight Retention within One Year: A Prospective Cohort Study in Vietnam

“…Separate linear regression analyses were performed to assess the association between weight retention at the two time points and each of the 3-month postpartum PA exposures, namely, total PA, light-intensity PA, moderate-intensity PA, household/caregiving, occupational, sports/exercise, and transportation, accounting for potential confounding factors. These confounding factors were selected based on our literature review with a consideration of the available information in our study; they were maternal age [17,23,24], education [17,24], formal employment [17,24], parity [17,23], mode of delivery [24], pre-pregnancy BMI [17,24], energy intake during pregnancy and total PA during pregnancy [29], gestational age and gestational weight gain [17,24]. The linear regression results were presented in terms of estimated regression coefficients together with their 95% confidence intervals (CI).…”

“…A multicenter prospective cohort study was conducted in Vietnam. Details of the study design, including sample size calculation and recruitment procedure, have been described elsewhere [23]. Briefly, a total of 2030 singleton pregnant women were recruited and followed up in three cities (Hanoi, Hai Phong, and Ho Chi minh City) between 2015 and 2017.…”

Postpartum Comfort and Breastfeeding Behavior of Primipara Obese and Non-Obese Mothers

“…They also declared that obese mothers have less self-ego and confidence. An immediate start of breastfeeding speeds up the involution process of the uterus by increasing the uterine contractions (6). A decreased success of obese mothers in breastfeeding results in the delay of the involution process of uterus, and this is thought to affect the level of comfort in the postpartum period.…”

“…Gestational diabetes and hypertensive diseases induced by pregnancy, which are observed frequently in maternal obesity, bring up the risks such as operative birth and anesthesia complications. An increase in the preterm birth rates, macrosomia, shoulder dystocia, and intrauterine, neonatal, or infant mortality are more frequent in obese mothers compared to mothers that have a normal body mass index (BMI) (3)(4)(5)(6)(7). In the literature, it was declared that maternal obesity was associated with fetal macrosomia, preterm birth, a low birth weight, neonatal hyperinsulinemia, and an increased need for neonatal intensive care (8,9).…”

Prelacteal and early formula feeding increase risk of infant hospitalisation: a prospective cohort study

“…A multicentre prospective cohort study was undertaken between August 2015 and December 2017 at six hospitals across three cities of Vietnam 16. A total of 2030 pregnant women were recruited during their antenatal care visits between 24 and 28 weeks of gestation.…”