2023
DOI: 10.1136/bmjopen-2022-067746
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Cohort profile: Using primary care data to understand Opioid Prescribing, Policy Impacts and Clinical Outcomes (OPPICO) in Victoria, Australia.

Abstract: PurposeThe OPPICO cohort is a population-based cohort based on non-identifiable electronic health records routinely collected from 464 general practices in Victoria, Australia, created with the aim of understanding opioid prescribing, policy impacts and clinical outcomes. The aim of this paper is to provide a profile of the study cohort by summarising available demographic, clinical and prescribing characteristics.ParticipantsThe cohort described in this paper comprises people who were aged at least 14 years a… Show more

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Cited by 9 publications
(6 citation statements)
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“…The study used the Population Level Analysis and Reporting (POLAR) dataset, a primary care dataset from 464 Victorian general practices across the eastern half of Australia, consisting of almost 700 000 de-identified patient records in which opioid analgesics were prescribed. 26 We accessed clinical records including prescriptions from eligible practices between January 2015 and December 2020. The data included age in 5-year brackets to protect patient confidentiality.…”
Section: Methodsmentioning
confidence: 99%
See 1 more Smart Citation
“…The study used the Population Level Analysis and Reporting (POLAR) dataset, a primary care dataset from 464 Victorian general practices across the eastern half of Australia, consisting of almost 700 000 de-identified patient records in which opioid analgesics were prescribed. 26 We accessed clinical records including prescriptions from eligible practices between January 2015 and December 2020. The data included age in 5-year brackets to protect patient confidentiality.…”
Section: Methodsmentioning
confidence: 99%
“…We defined our cohort on the basis of the following criteria: Patients (1) were ≥19 years of age at cohort entry; (2) had received at least 6 months of continuous opioid prescriptions (operationalized as having a gap of fewer than 60 days between subsequent prescriptions, based on the standard supply of opioids in Australia 26 ) ( Figure 1A ); (3) had received a stable dosage level during the 6-month baseline period (operationalized as the average daily opioid dose during any single month during the 6-month baseline period that did not vary by more than 10% from the average baseline dose, defined as the average of the total dose prescribed during the 6-month baseline period) ( Figure 2 ); (4) had an absence of terminal illness or cancer diagnoses (other than non-melanoma skin cancer) in the 12 months before and 12 months after the index date; (5) had an absence of opioid prescriptions for opioid replacement therapy (such as high-dose sublingual buprenorphine and buprenorphine-naloxone, methadone liquid) in the 12 months before and 12 months after the index date; and (6) had at least one clinic activity (eg, general practitioner visit or telehealth) or medication data recorded within 90 days after the date of the last opioid prescription ( Figure 1B ). This latter criterion examining activity within a 90-day window after an opioid taper was deemed necessary to distinguish between discontinuation of opioid therapy and disenrollment from the medical practices.…”
Section: Methodsmentioning
confidence: 99%
“…Data were sourced from all 464 participating general practices within the POLAR dataset, which are located in the south‐east of Victoria, and are situated within three of Victoria's Primary Health Networks or health regions; Gippsland, East Melbourne and Southeast Melbourne. Victoria has a total of six Primary Health Networks; the three included in the current study comprise both metropolitan and rural regions and represent half of the Victorian population [ 24 ].…”
Section: Methodsmentioning
confidence: 99%
“…Non‐identifiable routinely collected data from electronic health records was extracted. Data were extracted for patients aged ≥16 years at cohort entry (1 January 2017), with at least one opioid prescription indicated for pain, which had been prescribed at POLAR sites between 1 April 2017 and 31 December 2020 [ 24 ] and excluded patients with a cancer diagnosis during the study period.…”
Section: Methodsmentioning
confidence: 99%
“…These hospital networks are located in the greater Melbourne metropolitan area and have catchments of nearly 2.6 million people, covering 40% of Victoria’s population, with their EDs managing around 500,000 presentations per year. The areas represented by these data are geographically, demographically, and socioeconomically diverse [ 27 ].…”
Section: Methodsmentioning
confidence: 99%