Coincident Pellucid Marginal Degeneration and Fuchs’ Endothelial Dystrophy

Abstract

Aim: We report a rare case of coincident pellucid marginal degeneration and Fuchs' endothelial dystrophy.Background: As far as the authors are aware there have been no previous reports of this combination of corneal disorders in the same patient.Case description: A 45-year-old woman presented with progressive pellucid marginal degeneration and Fuchs' endothelial dystrophy. Progressive changes in corneal topography and specular microscopy imaging have been documented over 13 years since presentation. Declining vision has been successfully managed in this patient, to date, with serial crescentic corneal wedge excision biopsies to maintain acceptable spectacle-corrected visual acuity. Conclusion:This rare combination of corneal disorders presents an interesting and unique challenge for surgical management in the future, where corneal decompensation and cataract are likely to become limiting factors for visual acuity.Clinical significance: This is the first report of coincident pellucid marginal degeneration and Fuchs' endothelial dystrophy.