Coinfection of Influenza Virus and Group A Streptococcus in an Adult Suspected with Infectious Mononucleosis by Epstein-Barr Virus Infection

Abstract

The patient was a 21 year-old male who showed high fever and an infl uenza virus B antigen positive nasal specimen. He was initially suspected as infl uenza-related bronchitis and pharyngitis by group A Streptococcus; however, his fever, sore throat and skin eruption did not improve although he was administered anti-infl uenza drugs and amoxicillin for four days. He was admitted to our hospital and underwent microbial and serological examinations. Serology indicated recent Epstein-Barr infections. His symptoms and fever declined during drug free observation. He was fi nally diagnosed as having a EpsteinBarr virus infection followed by coinfection of infl uenza B and group A Streptococcus with penicillin allergy, which may be relatively common in adults, and should be kept in mind.