2021
DOI: 10.3390/molecules26071903
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Cold Plasma Systems and Their Application in Surface Treatments for Medicine

Abstract: In this paper, a review of cold plasma setups and the physical and chemical processes leading to the generation of active species is presented. The emphasis is given to the interaction of cold plasmas with materials used in medical applications, especially medical implants as well as live cells. An overview of the different kinds of plasmas and techniques used for generation of active species, which significantly alter the surface properties of biomaterials is presented. The elemental processes responsible for… Show more

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Cited by 89 publications
(48 citation statements)
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“…The phrase “plasma treatment” summarizes numerous methods/processes that generate (partially) ionized gas and/or radicals, which are frequently applied to various materials for surface modification, for example, for surface hydrophilization. [ 8,9 ] However, plasma processes often require specialized devices to provide either low ambient pressure (or even vacuum) [ 8 ] or high treatment temperatures (greater than or equal to several hundred degrees Celsius) [ 9 ] , and these harsh conditions are not always suitable. For instance, when the inside of a hollow, flexible sample (like a balloon) or temperature‐sensitive materials (i.e., most polymeric materials based on, e.g., polymethylmethacrylate, polystyrene, or polyvinylchloride) is to be treated, a different approach needs to be chosen.…”
Section: Introductionmentioning
confidence: 99%
“…The phrase “plasma treatment” summarizes numerous methods/processes that generate (partially) ionized gas and/or radicals, which are frequently applied to various materials for surface modification, for example, for surface hydrophilization. [ 8,9 ] However, plasma processes often require specialized devices to provide either low ambient pressure (or even vacuum) [ 8 ] or high treatment temperatures (greater than or equal to several hundred degrees Celsius) [ 9 ] , and these harsh conditions are not always suitable. For instance, when the inside of a hollow, flexible sample (like a balloon) or temperature‐sensitive materials (i.e., most polymeric materials based on, e.g., polymethylmethacrylate, polystyrene, or polyvinylchloride) is to be treated, a different approach needs to be chosen.…”
Section: Introductionmentioning
confidence: 99%
“…The surface modification of polymer films by plasma is the most effective method of uniform and controlled treatment. The surface energy of the films is controlled to enhance the wettability and adhesion of coatings by plasma treatment under different processing conditions [ 14 ].…”
Section: Introductionmentioning
confidence: 99%
“…Compared with most other treatments, a significant advantage of plasma surface modification, compared with most other treatments, is that it is free of harmful sub-products from the operation process and does not destroy the bulk structure of materials [ 37 , 42 , 43 ]. To enhance the different applications of materials, surface modification plays a critical role in various fields such as optical, electronics, automotive, aerospace, textile industry, packaging technology, 3D printing, pharmaceutical, and medical [ 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 ].…”
Section: Introductionmentioning
confidence: 99%