Colistin resistance in carbapenem non-susceptible Acinetobacter baumanii in a tertiary care hospital in India: clinical characteristics, antibiotic susceptibility and molecular characterization

Rout, Bidyut Prava; Dash, Sumesh Kumar; Otta, Sarita; Behera, Birasen; Praharaj, Ira; Sahu, Kundan Kumar

doi:10.1007/s11033-023-08982-5

Cited by 2 publications

(1 citation statement)

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“…Additionally, these strains often exhibit resistance to aminoglycosides via strA and srtB genes. Clinical samples, water and soil, turkey and chicken meat [40,52,75,76] In contrast, the prevalence of resistance genes appears lower in A. baumannii isolates from non-hospital environments. However, a study in Germany reported a concerning trend: isolates from powdered milk displayed universally high resistance to chloramphenicol and oxacillin [35].…”

Section: Other Sitesmentioning

confidence: 99%

Acinetobacter baumannii, a Multidrug-Resistant Opportunistic Pathogen in New Habitats: A Systematic Review

Ahuatzin-Flores,

Torres,

Chávez-Bravo

2024

Microorganisms

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In recent years, humanity has begun to face a growing challenge posed by a rise in the prevalence of antibiotic-resistant bacteria. This has resulted in an alarming surge in fatalities and the emergence of increasingly hard-to-manage diseases. Acinetobacter baumannii can be seen as one of these resilient pathogens due to its increasing prevalence in hospitals, its resistance to treatment, and its association with elevated mortality rates. Despite its clinical significance, the scientific understanding of this pathogen in non-hospital settings remains limited. Knowledge of its virulence factors is also lacking. Therefore, in this review, we seek to shed light on the latest research regarding the ecological niches, microbiological traits, and antibiotic resistance profiles of Acinetobacter baumannii. Recent studies have revealed the presence of this bacterium in a growing range of environmental niches, including rivers, treatment plants, and soils. It has also been discovered in diverse food sources such as meat and vegetables, as well as in farm animals and household pets such as dogs and cats. This broader presence of Acinetobacter baumannii, i.e., outside of hospital environments, indicates a significant risk of environmental contamination. As a result, greater levels of awareness and new preventive measures should be promoted to address this potential threat to public health.

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