2014
DOI: 10.14745/ccdr.v40i17a04
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Collaboration on a public health-driven vaccine initiative

Abstract: Disease surveillance can be used as an opportunity to determine priorities for research and the development of new therapeutics. This is evident in the work underway to develop a new vaccine to combat a serious invasive childhood disease: Haemophilus influenzae serotype a (Hia).

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Cited by 8 publications
(5 citation statements)
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“…Individuals residing in Canada’s north have unique health care needs that require government leadership and initiatives to ensure that they are met. To this end, a collaboration between the Public Health Agency of Canada, the National Research Council and the Northern Ontario School of Medicine launched a project in 2013, with the goal of developing a vaccine against HiA and a better understanding of HiA epidemiology through improved surveillance ( 21 ).…”
mentioning
confidence: 99%
“…Individuals residing in Canada’s north have unique health care needs that require government leadership and initiatives to ensure that they are met. To this end, a collaboration between the Public Health Agency of Canada, the National Research Council and the Northern Ontario School of Medicine launched a project in 2013, with the goal of developing a vaccine against HiA and a better understanding of HiA epidemiology through improved surveillance ( 21 ).…”
mentioning
confidence: 99%
“…In addition, the lack of a vaccine and the lack of published guidelines for the prophylaxis of contact exposure may represent a gap in our public health system for an emerging pathogen in a vulnerable population. Therefore, further population-based surveillance studies to identify those who may be at risk of this infection may help us to understand the epidemiology of invasive Hia infections as well as to pave the way for potentially developing a Hia monovalent or Hia–Hib bivalent vaccine for the protection of populations at risk of exposure to this pathogen ( 38 , 39 ).…”
Section: Discussionmentioning
confidence: 99%
“…A new H. influenzae type a vaccine is currently being developed in Canada (by the National Research Council, Public Health Agency of Canada and Northern Ontario School of Medicine) in collaboration with the U.S. Centers for Disease Control and Prevention, and it is anticipated that it may significantly alleviate the burden of this disease in vulnerable populations similar to what has happened as a result of universal paediatric immunization against H. influenzae type b ( Desai et al , 2014 ). However, before this vaccine can become available for immunization of vulnerable populations several important challenges have to be addressed.…”
Section: Discussionmentioning
confidence: 99%
“…Research is currently being carried out to determine why indigenous populations in North America are more prone to these infections and whether a H. influenzae type a vaccine may be required to control invasive H. influenzae type a disease in susceptible populations (Desai et al , 2014). …”
Section: Introductionmentioning
confidence: 99%
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