Collagen-Based Fibrillar Multilayer Films Cross-Linked by a Natural Agent

Chaubaroux, Christophe; Vrana, Nihal Engin; Debry, Christian; Schaaf, Pierre; Senger, Bernard; Voegel, Jean‐Claude; Haïkel, Youssef; Ringwald, Christian; Hemmerlé, Joseph; Lavalle, Philippe; Boulmedais, Fouzia

doi:10.1021/bm300529a

Cited by 73 publications

(85 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The pH value 7 and temperature above 40°C enhance the rate of reaction to form genipin dimer between polymers. The proposed formation structure of blue pigments (genipin dimer) from genipin is shown in previous reports (Chaubaroux et al 2012; Wang et al 2012). …”

Section: Introductionsupporting

confidence: 60%

Porosity and dielectric properties as tools to predict drug release trends from hydrogels

Raja

Fathima

2014

SpringerPlus

View full text Add to dashboard Cite

Conventional studies on hydrogel properties such as viscosity, pH and swelling provide information without treating the components of hydrogel, viz., water and polymer individually. Water and hydrophilic polymers need to be studied individually to understand their relationship with each other to relate their influence on drug release. In this context, we have assigned the combination of porosity and dielectric properties as tools to explore the hydrogels. Porosity and dielectric properties have been analyzed using thermoporometry and alternative current impedance measurements, respectively. A well-known hydrogel genipin cross linked gelatin-chitosan (GC) composite, with catechin as model drug has been studied. The increasing concentration of chitosan in the hydrogel composites led to increase in bound water content and incorporation of charge entrapping moieties. Controlled and medium drug release are observed for GC1 whereas the native hydrogels and composites with lower ratio of chitosan yield immediate release and composites with higher ratio effects in slow release for limited duration (9 hours) of drug delivery process. This trend of drug release is in accordance with the results obtained from porosity and dielectric properties where reduction in pore radii to lower range and increase in relaxation time of polymeric components were observed at higher concentration of chitosan. Thus, these properties can be judiciously used for predicting drug release and designing biomaterials according to it.

show abstract

Section: Introductionsupporting

confidence: 60%

Porosity and dielectric properties as tools to predict drug release trends from hydrogels

Raja

Fathima

2014

SpringerPlus

View full text Add to dashboard Cite

show abstract

“…Another reagent is the genipin, a natural molecule extracted from the fruits of Gardenia jasminoides (Endo and Taguchi 1973;Song et al 2009). As its toxicity seems limited, this molecule was investigated as a cross-linking agent in many biological applications (Chaubaroux et al 2012). In recent works, Silva et al (2014) and Nogueira Silva et al (2015) have characterized the casein micelles cross-linked by genipin.…”

Section: Chemical Reticulationmentioning

confidence: 99%

Modifications of structures and functions of caseins: a scientific and technological challenge

Broyard

Gaucheron

2015

Dairy Sci. & Technol.

264

133

View full text Add to dashboard Cite

Casein molecules are used in food industry as ingredients. They can be used as isolated forms and under micellar form consisting in an association of different casein molecules and calcium phosphate. In this review, after a brief reminder of the main characteristics of casein molecules and casein micelles, the modifications of caseins induced by physical, chemical, and enzymatic actions are reported. The resulting new physicochemical properties (mineral and casein compositions, charge, hydrophobicity, aggregation state, and morphology) and techno-functionalities (heat stability, viscosity, gelation, emulsifying, and foaming properties) are described and discussed with a special attention paid to the results obtained in our laboratory since several decades.

show abstract

“…In first approximation, the diminution of the normalized frequency shift, -f/ν, is be related with a growth of the adsorbed mass on the crystal. 40 …”

Section: Monitoring Of the Build-up Process By Quartz Crystal Microbamentioning

confidence: 99%

Immunomodulation with Self-Crosslinked Polyelectrolyte Multilayer-Based Coatings

et al. 2016

Self Cite

View full text Add to dashboard Cite

(2016) Immunomodulation with self-crosslinked polyelectrolyte multilayer-based coatings. Biomacromolecules, 17 (6). pp. 2189 -2198 . ISSN 1525 Access from the University of Nottingham repository: http://eprints.nottingham.ac.uk/34683/1/Knopf-Marques%20et%20al%202016%20Revised %20final.pdf Copyright and reuse:The Nottingham ePrints service makes this work by researchers of the University of Nottingham available open access under the following conditions. This article is made available under the Creative Commons Attribution Non-commercial licence and may be reused according to the conditions of the licence. For more details see: http://creativecommons.org/licenses/by-nc/2.5/ A note on versions:The version presented here may differ from the published version or from the version of record. If you wish to cite this item you are advised to consult the publisher's version. Please see the repository url above for details on accessing the published version and note that access may require a subscription. . Moreover, we demonstrate that crosslinking PLL/HA film using HA-aldehyde is already effective by itself to limit inflammatory processes.Finally, this functionalized self-crosslinked PLL/HA-aldehyde films constitutes an innovative and efficient candidate for immunomodulation of any kind of implants of various architecture and properties.

show abstract

Collagen-Based Fibrillar Multilayer Films Cross-Linked by a Natural Agent

Cited by 73 publications

References 37 publications

Porosity and dielectric properties as tools to predict drug release trends from hydrogels

Porosity and dielectric properties as tools to predict drug release trends from hydrogels

Modifications of structures and functions of caseins: a scientific and technological challenge

Immunomodulation with Self-Crosslinked Polyelectrolyte Multilayer-Based Coatings

Contact Info

Product

Resources

About