Collagen-based hydrogels cross-linked via laccase - mediated system incorporated with Fe3+ for wound dressing

An antibacterial and healing-promoting collagen fibril constructed by the simultaneous strategy of fibril reconstitution and ε-polylysine anchoring for infected wound repair

“…The experimental procedure referred to the method of Yang. 44 The collagen fibrils were prepared on a 24-well plate using 200 μL of blended collagen solutions, following the method described in section 2.2. Subsequently, the samples were purified and irradiated.…”

“…The morphology staining of cell growth was implemented according to the method described by Yang. 44 The samples were prepared as described in section 2.6.2. 100 μL of L929 fibroblasts were then directly seeded on the surface of the purified samples for 3 days were fixed with paraformaldehyde at 4 °C for 4 h, and the cells on the samples were stained with fluorescein isothiocyanate phalloidin (TRITC phalloidin), followed by co-incubation for another 30 min at 37 °C in darkness.…”

Antibacterial, Fatigue-Resistant, and Self-Healing Dressing from Natural-Based Composite Hydrogels for Infected Wound Healing

“…24 With an extracellular matrix (ECM)-like microstructure, hydrogels can maintain a moist environment during wound healing and are further used as a platform to load with diverse antibacterial drugs for combating microorganism infection. 25−27 Recently, naturalbased hydrogel dressings consisting of collagen, 28 chitosan, 29,30 alginate, 31 cellulose, 32 etc. have been considered highly competitive candidates for treating infected wounds.…”

“…Flourishing advances in biomedical materials have witnessed an ever-growing concept of hydrogel dressings. , Hydrogels, as a class of soft matter, are appealing with the features of high-water uptake, large volume change, good mechanical compliance, and biocompatibility . With an extracellular matrix (ECM)-like microstructure, hydrogels can maintain a moist environment during wound healing and are further used as a platform to load with diverse antibacterial drugs for combating microorganism infection. − Recently, natural-based hydrogel dressings consisting of collagen, chitosan, , alginate, cellulose, etc. have been considered highly competitive candidates for treating infected wounds.…”

Injectable, Antioxidative, and Tissue‐Adhesive Nanocomposite Hydrogel as a Potential Treatment for Inner Retina Injuries

“…Various strategies have been employed in the past to functionalize gelatin including covalent attachment of chemical groups [ 31 , 32 ] and photo‐crosslinking techniques. [ 33 , 34 , 35 ] In our study, however, we have taken a unique approach by grafting cinnamic acid onto the gelatin sequence, thereby enabling the formation of a novel photo‐crosslinkable hydrogel, referred to as GelCA. This modification not only introduces new properties to the gelatin‐based hydrogel but also enhances its suitability for applications in tissue engineering and regenerative medicine.…”