C ollagen is the most abundant protein in the animal kingdom and is a key component of the extracellular matrix (ECM). Collagen is produced from both natural and synthetic resources. Natural resources are the best resources. Collagen has attracted wide attention in several fields due to its abundance, low cost, and exciting physical and chemical properties, especially, biocompatibility and biodegradability. However, collagen suffers from weak physical and chemical characteristics (mechanical strength, thermostability and resistance to enzyme). As a result, collagen must be modified throughout the processing process. collagen is an ecofriendly resource that can be used to produce multifunctional, recyclable, biocompatible, and biodegradable materials that are ideal for new technologies in materials science, biomedicine, and environmental remediation.