2022
DOI: 10.1002/jbio.202100365
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Collagen signature as a novel biomarker to predict axillary lymph node metastasis in breast cancer using multiphoton microscopy

Abstract: Accurate identification of axillary lymph node (ALN) status is crucial for tumor staging procedure and decision making. This retrospective study of 898 participants from two institutions was conducted. The aim of this study is to evaluate the diagnostic performance of clinical parameters combined with collagen signatures (tumor‐associated collagen signatures [TACS] and the TACS corresponding microscopic features [TCMF]) in predicting the probability of ALN metastasis in patients with breast cancer. These findi… Show more

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