Collagenous Colitis Report of three cases and review of the literature.

Janssens, Laurens; Eycken, Maurits; Vanderschueren, Dirk; Baarle, A. Van; Beelaerts, W.; Denekens, Joke; Baere, H. De

doi:10.1080/17843286.1988.11717904

Acta Clinica Belgica

1988

DOI: 10.1080/17843286.1988.11717904

|View full text |Cite

Collagenous Colitis Report of three cases and review of the literature.

Laurens Janssens¹,

Maurits Eycken²,

Dirk Vanderschueren³

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2009

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Cyclooxygenase‐2 immunoreactivity in collagenous colitis

Wildt¹,

Rumessen²,

Csillag³

et al. 2009

APMIS

View full text Add to dashboard Cite

Collagenous colitis (CC) is an inflammatory bowel disease of unknown aetiology and pathogenesis. In ulcerative colitis and Crohn's disease, prostaglandins may be involved in the pathogenesis of inflammation, and increased expression of cyclo-oxygenase-2 (COX-2) has been detected. The purpose of this study was to examine the presence and cellular localization of COX-2 in colonic mucosa of patients with CC. Using immunohistochemistry, immunoflouresence and Western blot analysis, COX-2 expression was evaluated in colonic mucosal biopsies from 10 patients with active untreated CC, and compared with samples from eight normal controls, and samples from eight patients with ulcerative colitis or Crohn's disease. Specimens from patients with CC expressed COX-2 protein in increased amounts compared with controls, but similar to patients with ulcerative colitis and Crohn's disease. COX-2 expression was localized to the mononuclear cells of the lamina propria. COX-2 expression was most evident in macrophages. Co-localization of COX-2 and macrophages was increased in number in comparison with controls. In conclusion COX-2 is expressed in increased amounts primarily in the macrophage subpopulation of the inflammatory infiltrate of lamina propria in CC. Increased recruitment of macrophages, increased expression of COX-2 and increased prostaglandin synthesis may be involved in the pathogenesis of CC.

show abstract

Cyclooxygenase‐2 immunoreactivity in collagenous colitis

Wildt¹,

Rumessen²,

Csillag³

et al. 2009

APMIS

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Collagenous Colitis Report of three cases and review of the literature.

Cited by 1 publication

References 0 publications

Cyclooxygenase‐2 immunoreactivity in collagenous colitis

Cyclooxygenase‐2 immunoreactivity in collagenous colitis

Contact Info

Product

Resources

About