Collagenous sprue cross-sectional imaging: a comparative blinded study

Al-Bawardy, Badr; Sheedy, Shannon P.; Herberts, Michelle; Murray, Joseph A.; Rubio–Tapia, Alberto; Rajan, Elizabeth; Hansel, Stephanie L.; Barlow, John M.; Fletcher, Joel G.; Fidler, Jeff L.

doi:10.1007/s00261-016-1007-1

Cited by 1 publication

(2 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…While Collagenous sprue was formally characterized in 1970, unfortunately little is known regarding the pathogenesis of the disease given its rarity [1,2], which impedes the formulation of a gold standard treatment plan. Clinically, CS is characterized by chronic diarrhea, mal absorption and weight loss.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Untitled

2023

Int J Rare Dis Disord

View full text Add to dashboard Cite

Collagenous sprue, a rare and poorly understood disease of the small bowel is characterized by progressive weight loss, chronic diarrhoea and malabsorption. Due to its rarity, it is often misdiagnosed as celiac disease as it presents in similar manner. However, collagenous sprue unlike celiac disease is often refractory to gluten free diet and has poor prognosis. The key distinction between collagenous sprue and celiac disease lies in the biopsy of the small bowel where collagenous sprue shows prominent sub epithelial collagen deposition. As it has the potential to progressively deteriorate resulting in severe malnourishment, timely diagnosis through microscopic and macroscopic evaluation is crucial for early intervention. Herein, we present the diagnostic odyssey of an 89-year-old female patient who came in with a 6 months history of weight loss and chronic diarrhoea. She was eventually diagnosed with collagenous sprue, however she had passed away 2 months later following her initial diagnosis.

show abstract

Section: Discussionmentioning

confidence: 99%

“…Collagenous Sprue (CS), an extremely rare disease affecting the small bowel with slightly over a hundred case reports published in the literature, was histologically characterized in 1970 [1,2]. CS affects more females than males (2:1), and most affected patients were middle age or elderly patients [3].…”

Section: Introductionmentioning

confidence: 99%

Untitled

2023

Int J Rare Dis Disord

View full text Add to dashboard Cite

show abstract

Collagenous sprue cross-sectional imaging: a comparative blinded study

Abstract: Imaging findings suggestive of mucosal malabsorption are commonly demonstrated in CS.

Cited by 1 publication

References 18 publications

Untitled

Untitled

Contact Info

Product

Resources

About