Collared peccary (Pecari tajacu ) are susceptible to porcine reproductive and respiratory syndrome virus (PRRSV)

Abstract

Collared peccary (Pecari tajacu) and pigs (Sus scrofa) are two members of superfamily Suoidea that coexist in the Americas and share some of the same viral infections. Although porcine reproductive and respiratory syndrome virus (PRRSV) is among the most impactful pathogens of swine on a worldwide basis, the susceptibility of peccaries to PRRSV has not been investigated. In this study, three peccaries were intramuscularly inoculated with a PRRSV-2 field virus. One PRRSV-inoculated pig served as a positive control and two pigs and one peccary as negative controls. Serum samples were collected at regular intervals over a 23-day observation period and tested by PRRSV rtRT-PCR and isotype-specific (IgM, IgA, IgG) PRRSV ELISAs. The detection of viremia (DPI 3-23) and a PRRSV-specific humoural immune response (≥DPI 10) supported the conclusion that collared peccary are susceptible to PRRSV. The results raise questions regarding the natural history of PRRSV in non-Sus members of superfamily Suoidea and, more broadly, their role in the evolution and ecology of PRRSV.

Structural comparison of CD163 SRCR5 from different species sheds some light on its involvement in porcine reproductive and respiratory syndrome virus-2 infection in vitro

“…PRRSV infection shows a strongly restricted tropism for host species and target cells. Swine, including domestic pigs and wild boar, are the only known hosts for PRRSV [ 14 – 19 ]. CD163-positive macrophages, particularly porcine alveolar macrophages (PAMs), are PRRSV primary target cells in vivo [ 20 ].…”

Hepatitis E Virus (HEV) infection in captive white‐collared peccaries ( Pecari tajacu ) from Uruguay

“…Therefore, this possibility and the existence of these immunosuppressive pathogens should be further investigated. Additionally, Pecari tajacu seems to be susceptible to PRRSV infection, and this is an important point, since this pathogen is widely distributed in Uruguay, at least in pigs (Molina‐Barrios et al., 2018; Ramos et al., 2018). And third, given that animal populations were closed, and individuals were not routinely extracted nor introduced in the enclosures until this work ended, which may have affected the dynamics of the disease, the different source (e.g.…”

Captive collared peccary carries ESBL-producing diarrheagenic Escherichia coli pathotypes

“…Collared peccaries have also been found to harbour classical swine fever virus (5%), porcine circovirus type 2 (7%) and vesicular stomatitis (33%). They also share pathogens with domestic and wild pigs (Sus scrofa) (Montenegro et al, 2018;Molina-Barrios et al, 2018).…”